Master's theses (KBM): Nye registreringer
Viser treff 381-400 av 890
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Purification and characterization of streptovoracin, a novel antibiotic produced by a Pseudomonas species isolated from the Oslo fjord
(Master thesis, 2019)Antibiotikaresistent Streptococcus pneumoniae er en av de 18 største bakterielle truslene verden står ovenfor. Bakterien er alene ansvarlig for oppunder 2 millioner dødsfall hvert år på verdensbasis. På grunn av stadig ... -
Synthesis of the Methyl Ester of MaR2n-3 DPA
(Master thesis, 2019)This master thesis presents the first synthesis of the methyl ester of the specialized pro-resolving mediator named MaR2n-3 DPA. The stereoselective synthesis is based on a Z-selective Lindlar reaction, a Sonogashira ... -
Characterization of Lactococcus garvieae from rainbow trout (Oncorhynchus mykiss) in Spain and Turkey
(Master thesis, 2019)Lactococcus garvieae is an emerging pathogen that causes mortalities in various farmed fish species, resulting in significant economic losses in aquaculture worldwide. The Gram-positive bacteria is pathogenic to both ... -
YthA : a lone ranger or team player in the cell envelope stress response of Lactococcus lactis IL1403?
(Master thesis, 2019)Considering the increasing problem of antibiotic-resistant pathogens emerging world- wide, research into novel antimicrobial substances that can become clinically relevant is now of the utmost importance. The small ... -
Characterization of a thermostable exolytic alginate lyase from hot vents in the Arctic Mid-Ocean Ridge
(Master thesis, 2019)Verdens behov for petroleumsprodukter øker stadig, men minkende oljereserver og miljøproblemer gjør at det bør prioriteres utvikling og bruk av alternative, fornybare ressurser. Bioraffinering dreier seg om å bruke biomasse ... -
Evaluation and optimization of procedures for HPV detection and genotyping in oral and urine samples in men
(Master thesis, 2019)Human papillomavirus (HPV) has been well established as a carcinogen in human epithelial cancers; especially in the uterin cervix. Head and neck cancers (HNC) are increasing worldwide despite global reduction in smoking. ... -
Benchmarking of metagenomic classification tools and storage stability of bioaerosol samples
(Master thesis, 2019)Air is a microbial habitat of crucial importance for public health. As such it is relevant for detection of potential epidemic or biothreat agents. The study of microbiological diversity in air through metagenomic analysis ... -
Genetisk og klinisk karakterisering av moyamoyasjukdom hos pasientar av skandinavisk opphav
(Master thesis, 2019)Innleiing Dei siste 15 åra har det vore stor utvikling av nye teknologiar for DNA-sekvensering. Dette har opna opp for mange nye bruksområde av desse teknologiane. Utviklinga av neste generasjons sekvensering (NGS) har ... -
Characterization of organic art materials by GC-MS
(Master thesis, 2019)Background: In conservation of old paintings, knowing the composition of the paint binder is of great importance. Some conservation techniques can be damaging to the paintings when it is applied to the wrong kind of paint. ... -
Mycobacterium tuberculosis culturomics : hunting for the key to more rapid and sensitive cultivation and rescue
(Master thesis, 2018)Tuberkulose (TB) er et stort folkehelseproblem som forårsakes av bakteriene tilhørende M. tuberculosis- komplekset (MTBC). Påvisning av mykobakterier i sputumprøver fra TBpasienter krever tid, spesielt hvis bakteriene er ... -
Implementation of a two-plasmid CRISPR/Cas9 system in Lactobacillus plantarum : a new approach in the development of a novel vaccine against Mycobacterium tuberculosis
(Master thesis, 2018)Tuberculosis (TB) is the leading cause of deaths from a single infectious agent, and in 2017 1.7 million people died from TB. To date the only available vaccine against the disease is the bacille Calmette-Guèrin (BCG) ... -
In silico exploration of stx2a-positive (STEC) and stx-negative Escherichia coli (STEC-LST)
(Master thesis, 2018)Escherichia coli er en harmløs bakterie som naturlig sameksisterer med mennesker og dyr i tarmen. E. coli-genomet er dynamisk og kan skape store interne endringer (rekombinasjon), overføre plasmider (konjugasjon), tilegne ... -
Measuring growth of denitrifiers in digestate using gas kinetics
(Master thesis, 2018)Denitrification is a microbial, anaerobic process reducing nitrogen oxyanions to gaseous products in a stepwise reaction that leads to a release of nitrous oxide gas to the atmosphere. Denitrification has four steps; NO3 ... -
Syntetiske studier av nye analoger av 2-metoksyøstradiol med antatt anti-cancer effekter
(Master thesis, 2018)I denne oppgaven har det blitt fremstilt analoger av østrogenmetabolitten 2-metoksyøstradiol. Det har totalt blitt syntetisert sju nye analoge forbindelser. Analogene ble fremstilt ved hjelp av ulike synteseveier. ... -
A new method for the synthesis of fatty acid amides
(Master thesis, 2018)The amide bond is an essential part of many natural products and is also found in a lot of today’s pharmaceuticals. The fatty acid amides are a group of natural products that has shown biological activity towards several ... -
Screening for antimicrobial agents against the fish pathogens, Streptococcus agalactiae and Yersinia ruckeri, in fermented fruit and vegetables
(Master thesis, 2018)Antibiotics have been used for a long period of time both for human and animal health, as well as economical benefits. Because of an emerging antibiotic resistance in pathogen microbes, there is an increasing need for new ... -
Immunotherapeutic targeting of tumor-associated macrophages
(Master thesis, 2018)The development of CAR T cell technology allows for MHC-independent recognition of a native target antigen by T cells. In august 2017, the first CD19-specific CAR T cell therapy was approved in the U.S. for the treatment ... -
Kjøkkenvaner og mattrygghet hos forbrukeren : fokus på krysskontaminering og hygiene etter håndtering av rå kylling
(Master thesis, 2018)Matbåren sykdom er et helsemessig og samfunnsøkonomisk problem. For å sikre trygg mat til alle, er det utformet en strategi som skal dekke hele matkjeden fra «jord/fjord til bord». Det er derimot vanskelig å kontrollere ... -
Identification of celiac disease related immunogenic peptides in Norwegian wheat types after ex vivo digestion
(Master thesis, 2018)Wheat has been part of human diet for centuries in the form of bread, pasta, cakes and pastries. There has been a lot of research to introduce better crop yield and disease resistant wheat varieties. Today’s wheat varieties ... -
On the application of machine learning techniques for phenotypic classification and clustering of heart failure patients
(Master thesis, 2018)In this thesis, we attempt to investigate how well various clustering algorithms (hierarchical clustering, k-means and expectation–maximization) perform in producing phenotypically distinct clinical patient groups (i.e. ...