• Characterization of Escherichia coli AlkB homologue 1 

      Asker, Gry (Master thesis, 2010-12-23)
      The DNA molecule is exposed to alkylating agents produced endogenously and in the environment. Cells have therefore developed several responses to alkylating damage including direct repair by oxidative demethylation. The ...
    • Isoforms, subcellular localization and role in survival of mammalian Endonuclease V 

      Thorgaard, Eirik (Master thesis, 2012-09-11)
      Our hereditary material, the DNA, is on a daily basis subjected to endogenous and exogenous agents that lead to DNA damage. Therefore it is essential for the genomic integrity that these damages are repaired efficiently. ...
    • Processing of apurinic/apyrimidinic (AP) sites in mammalian cells 

      Nawaz, Meh Sameen (Master thesis, 2012-09-12)
      Abstract The integrity of deoxyribonucleic acid (DNA) is continuously challenged by endogenous and exogenous DNA damaging agents. Mutagenic and cytotoxic apurinic/apyrimidinic (AP) sites are amongst the most frequently ...