Doctoral theses (KBM): Nye registreringer
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Prokaryote classification : method development and novel insight in 16S ribosomal RNA-based classification
(PhD Thesis;2016:95, Doctoral thesis, 2016)The main objective of this thesis is the improvement of prokaryotic classification based on the 16S ribosomal RNA. As a result of the shift in sequencing technology, generating enormous amounts of sequencing data and the ... -
Biochemical investigation of catalysis by lytic polysaccharide monooxygenases
(PhD Thesis;2016:69, Doctoral thesis, 2018-05-04)Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that catalyze the oxidative cleavage of glycosidic bonds in the presence of dioxygen and an external electron donor. Currently, these enzymes are ... -
A study of human chitinases with respect to the importance of surface exposed aromatic residues and carbohydrate-binding modules in substrate degradation and role in inflammations
(PhD Thesis;2015:63, Doctoral thesis, 2018-05-03)Chitin is an insoluble, linear polymer consisting of β-1, 4-linked N-acetyl-glucosamine units tightly packed in a crystalline structure. It is the second most abundant polysaccharide in nature, after cellulose, with an ... -
Health communication with adolescents and young adults to promote healthy eating
(PhD Thesis;2016:30, Doctoral thesis, 2018-05-03)Enhancing health communication with adolescents and young adults for health promotion, including a healthier diet, is essential. Nutrition labeling, applications (apps), and school environment are three channels for health ... -
Gene regulation and the emergence of phenotypes – a network approach
(PhD Thesis;2016:52, Doctoral thesis, 2018-05-03)The emergence of complex traits in living organisms has been of interest to biologists since the early days of biology. Domestication and breeding has resulted in the most remarkable transformations, such as the grass ... -
Linear multiresponse models : theoretical developments and applications in porcine
(PhD Thesis;2016:34, Doctoral thesis, 2018-05-03)The main topic of this PhD–thesis is how to minimize the prediction error for multi–response linear regression models. Two different applications are analysed, (i) bivariate response with missing data and (ii) image analysis ... -
Regulation of expression, purification and structural determination of the cross-wall splitting protein PcsB in Streptococcus pneumoniae
(PhD Thesis;2015:8, Doctoral thesis, 2018-04-24)The human pathogen Streptococcus pneumoniae causes approximately 1.6 million deaths per year. Hence, it is of great concern that the bacterium`s resistance against antibiotics has increased dramatically in recent decades. ... -
Garvicin KS, a bacteriocin with wide inhibitory spectrum and potential application
(PhD Thesis;2018:04, Doctoral thesis, 2018)In this study, we screened for bacteriocin producer(s) from a large collection of bacterial isolates (over 1800) obtained from raw milk using a panel of indicator strains of different bacterial species and genera. Fourteen ... -
Staphylococcus aureus from milk and milk products in Ethiopia : prevalence, enterotoxigenic potential, antibiotic resistance and spa types
(PhD Thesis;2016:48, Doctoral thesis, 2017-12-12)Milk production in Ethiopia is increasing. However, due to unhygienic and traditional milk production and processing practices the issue of milk safety remains a challenge. If these safety issues are not properly addressed, ... -
Fungal aerosols : characterization and immunodetection of fungal fragments
(PhD Thesis;2015:26, Doctoral thesis, 2017-11-30)Indoor environments with high moisture problems often reveal colonization of indoor materials by fungi with release of airborne fungal particles. Exposure to airborne fungal particles has been associated with various ... -
Factors influencing the processing quality of potatoes : development of analytical tools for process monitoring and optimization
(PhD Thesis;2015:30, Doctoral thesis, 2017-11-30)Potatoes are notoriously heterogeneous, and manufacturers of processed potato products are therefore faced with a number of challenges during processing. The motivation behind this thesis is to reduce waste and cut production ... -
A detailed study of substrate positioning in family 18 chitinases
(PhD Thesis;2011:41, Doctoral thesis, 2011)Chitin is a linear polymer consisting of β-1,4-linked N-acetyl-glucosamine (GlcNAc; A) units tightly packed in a crystalline structure. It is produced by living organisms in large quantities per year and is a structural ... -
Minimizing photooxidation in dairy products by tailor made light barrier properties in packaging materials
(PhD Thesis;2011:47, Doctoral thesis, 2011)Photooxidation is one of the major causes of food quality deterioration. Packaging is a common tool to protect against light and consequently prolong the shelf life of food. Transparent packaging materials are being widely ... -
Regulation of energy metabolism in enterococcus faecalis studied by transcriptome, proteome and metabolome approaches
(PhD Thesis;2011:48, Doctoral thesis, 2011)Lactic Acid Bacteria (LAB) are widely used as starter culture in food fermentation. Among LAB also pathogenic bacteria are found particular in enterococci and streptococci. Enterococcus faecalis is a gut commensal bacterium ... -
Multivariate analysis as a tool for understanding and reducing complexity of mathematical models in systems biology
(PhD Thesis;2011:34, Doctoral thesis, 2011)In the area of systems biology, technologies develop very fast, which allows us to collect massive amounts of various data. The main interest of scientists is to receive an insight into the obtained data sets and discover ... -
Knowledge-based methods handling complex dependency structures : applications to gene expression data
(PhD Thesis;2011:46, Doctoral thesis, 2011)Microarray gene expression data are usually associated with a large number of correlated variables measured on few samples. This type of data typically contain high levels of noise, and the biological signals may be difficult ... -
Characterization of fecal lactic acid bacteria isolated from healthy Ethiopian infants : bacteriocin production and antibiotic suscepebility
(PhD Thesis;2011:55, Doctoral thesis, 2011)In this thesis lactic acid bacteria (LAB) were isolated from fecal samples of healthy Ethiopian infants, identified to species level, screened for bacteriocin production and tested for antibiotic susceptibility. Enterococci ... -
Identification of androstenone sensitive subjects and their evaluation of different androstenone and skatole tainted meat products
(PhD Thesis;2011:12, Doctoral thesis, 2011)Castration of entire male pigs is widely used in Norway to prevent the unpleasant odour/flavour that may occur in meat from boars. Castration of entire male pigs is expected to be prohibited in Norway (and in Europe) in ... -
Class II bacteriocins : target recognition, resistance and immunity
(PhD Thesis;2011:11, Doctoral thesis, 2011)Bacteriocins are bacterial antimicrobial peptides which are active against strains often closely related to the producer. Bacteriocins produced by food grade lactic acid bacteria are considered promising for applications ... -
A study of mechanisms involved in the pathogenicity of Enterococcus faecalis by DNA microarrays
(PhD Thesis;2010:54, Doctoral thesis, 2010)Traditionally considered a harmless commensal of the mammalian gastrointestinal tract, Enterococcus faecalis now rank among the leading causes of nosocomial infections worldwide. Several genetic determinants enhancing the ...