Doctoral theses (KBM)
Unless otherwise stated on the individual theses, the works in this collection are licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Recent Submissions
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Investigating molecular determinants of lytic polysaccharide monooxygenase (LPMO) reactions
(PhD Thesis;2024:61, Doctoral thesis, 2024)Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that can activate inert C-H bonds in polysaccharides with bond energies close to 100 kcal∙mol-1. This capability has sparked interest in the use of LPMOs ... -
The gut microbiota from the general population during the first year of life
(PhD thesis;2022:67, Doctoral thesis, 2022)The human gut microbiota consists of a complex community of microorganisms with bacteria as the major resident. Their role in the gut can be viewed as an extension of our genes and is often compared to a human organ. The ... -
Impact of FODMAP and reactive oxygen species (ROS) on the gut microbiota : implications for gut health
(PhD Thesis;2024:21, Doctoral thesis, 2024)FODMAPs (fermentable oligo-, di- and mono-saccharides, and polyols) are dietary short-chain carbohydrates which have been suspected to trigger gastrointestinal symptoms in individuals with irritable bowel syndrome (IBS) ... -
Virulence and antibiotic resistance in Pseudomonas aeruginosa
(PhD Thesis;2024:55, Doctoral thesis, 2024)Pseudomonas aeruginosa is an opportunistic pathogen that poses a considerable threat to human health because of its capacity to cause severe and potentially life-threatening infections. A thorough understanding of the ... -
Metabolic modeling for aquaculture
(PhD thesis;2024:6, Doctoral thesis, 2024)Farmed Atlantic salmon is Norway’s second lagest export, and by 2030 aquaculture will provide most of the world’s food fish. Salmon is a highly resource-efficient production animal, but scarce feed resources require action ... -
Kelp as food ingredient : processing and product evaluation
(PhD Thesis;2024:43, Doctoral thesis, 2024)Developing a more sustainable food production system calls for innovations, including increased use of underutilized resources and introduction of novel ingredients in food. Cultivation of seaweed is environmentally friendly ... -
Developing Lactiplantibacillus as a delivery vehicle for medicinal proteins
(PhD Thesis;2024:39, Doctoral thesis, 2024)Microbial vaccine vehicles have the potential to become the cheapest and safest option for vaccination due to needle-free administration, and easy production, storage, and distribution. Utilization of non-pathogenic food ... -
Exploring food-derived bioactives through ex vivo digestion, peptidomic profiling and in silico modelling
(PhD Thesis;2024:40, Doctoral thesis, 2024)Food bioactives are defined as substances in food that interact with human biological processes, affecting body functions or conditions and ultimately health. Bioactive peptides (BAPs) deriving from dietary proteins can, ... -
Modifying cellulose fibers with lytic polysaccharide monooxygenases (LPMOs)
(PhD Thesis;2024:42, Doctoral thesis, 2024)This PhD thesis encompasses studies of how lytic polysaccharide monooxygenases (LPMOs) may be used for enzymatic modification and functionalization of cellulose for the development of renewable biomaterials. The thesis ... -
Interplay between LPMOs and cellulases during enzymatic degradation of cellulose : effects of time, lignin, light and substrate concentration
(PhD thesis;2024:33, Doctoral thesis, 2024)The recent discovery of lytic polysaccharide monooxygenases (LPMOs) marked a paradigm shift in our understanding of enzymatic saccharification of lignocellulosic biomass. Under aerobic conditions, interactions between ... -
DNA methylation in a nutritional and social context : a study of cytosine modifications in honey bee (Apis mellifera) workers
(PhD Thesis;2023:10, Doctoral thesis, 2023)Intergenic DNA methylation is widespread in both the animal and plant kingdoms. Its presence in exons is believed to be dynamic and suggests its involvement in the regulation of alternative splice variants. In addition, ... -
Objective methods of classification for beef- and pork carcases as a basis for evaluation of carcase yield
(PhD Thesis;2024:13, Doctoral thesis, 2024)Yield within the meat industry refers to the ratio and weight of tissues from the carcase. Carcase classification gives each carcase grades that determine the price paid for the carcase. Two aspects are especially important ... -
Exploring variability of perceptions and heterogeneity of opinions
(Dr. Philos. thesis;2023:2, Doctoral thesis, 2023)The manuscripts in this thesis introduce new sensometric methods. Some methods investigate the variability of perceptions in sensory studies involving trained or consumer panels. Other methods explore the heterogeneity of ... -
An investigation of the interplay between in situ hydrogen peroxide production and catalytic efficiency in lytic polysaccharide monooxygenase reactions
(PhD thesis;2022:27, Doctoral thesis, 2022)Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that catalyze oxidative depolymerization of recalcitrant carbohydrate substrates, such as chitin and cellulose. LPMOs have received much attention from ... -
Bacteriocins : from discovery to characterization and applications
(PhD thesis;2023:74, Doctoral thesis, 2023)Multidrug resistant bacteria have become a major concern in both human and veterinary medicine. Due to the waning efficacy of many antibiotics, new antimicrobial agents are needed. Bacteriocins are ribosomally ... -
Local food entrepreneurs in Norway : case studies on successful practices for network learning and market development
(PhD Thesis;2023:23, Doctoral thesis, 2023)Local food has been compared to a "quiet culinary revolution" in Norway, one initiated by a governmental strategy more than 20 years ago. The aim was to provide more local specialtiesꟷ"food and drink products with a ... -
The site-2-protease RseP as a novel antimicrobial target
(PhD Thesis;2023:22, Doctoral thesis, 2023)The discovery and development of antibiotics have revolutionized modern medicine. Today, several decades after the first patients were treated with antibiotics, bacterial infections are again becoming increasingly difficult ... -
Cheese-making efficiency affected by protein source in concentrate feed for dairy cows and their αS1-κ-casein genotypes
(PhD Thesis;2023:32, Doctoral thesis, 2023)Evaluation of cheese-making efficiency is important for the dairy industry for profitability and sustainability reasons. Milk with a beneficial composition that favours good coagulation properties and a higher cheese yield ... -
Small intestinal microbiota – Regulation by reactive oxygen species and influence of diet
(PhD Thesis;2022:5, Doctoral thesis, 2022)Over the last years multiple studies have analyzed the impact of intestinal microbiota on health. Certain changes in the composition of the microbial population in the intestine have been associated with several diseases ... -
Leveraging H2O2-fuelled activity of lytic polysaccharide monooxygenases in cellulase cocktails for improved bioprocessing of lignocellulosic biomass
(PhD Thesis;2022:29, Doctoral thesis, 2022)Rapid action is critical to reduce anthropogenic CO2 emissions in order to reach climate targets. Fossil fuel use in high emission sectors like the energy and chemical industry should therefore be reduced and replaced by ...
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