Browsing Doctoral theses (KBM) by Document Types "Doctoral thesis"
Now showing items 1-20 of 123
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A detailed study of substrate positioning in family 18 chitinases
(PhD Thesis;2011:41, Doctoral thesis, 2011)Chitin is a linear polymer consisting of β-1,4-linked N-acetyl-glucosamine (GlcNAc; A) units tightly packed in a crystalline structure. It is produced by living organisms in large quantities per year and is a structural ... -
A study of human chitinases with respect to the importance of surface exposed aromatic residues and carbohydrate-binding modules in substrate degradation and role in inflammations
(PhD Thesis;2015:63, Doctoral thesis, 2018-05-03)Chitin is an insoluble, linear polymer consisting of β-1, 4-linked N-acetyl-glucosamine units tightly packed in a crystalline structure. It is the second most abundant polysaccharide in nature, after cellulose, with an ... -
A study of mechanisms involved in the pathogenicity of Enterococcus faecalis by DNA microarrays
(PhD Thesis;2010:54, Doctoral thesis, 2010)Traditionally considered a harmless commensal of the mammalian gastrointestinal tract, Enterococcus faecalis now rank among the leading causes of nosocomial infections worldwide. Several genetic determinants enhancing the ... -
An explorative study of Enterococcus faecalis transcriptional responses to infection-relevant growth environments
(PhD Thesis;2010:10, Doctoral thesis, 2010)Enterococcus faecalis is commonly found in the gastrointestinal tract of humans. It is also an opportunistic pathogen and one of the leading causes of nosocomial infections worldwide. The treatment of E. faecalis infections ... -
Antifungal activity of chitosan/chitooligosaccharides alone and in combination with chemical fungicides against fungal pathogens
(PhD Thesis;2013:12, Doctoral thesis, 2013)Botrytis cinerea Pers. ex Fr. is an economically important pathogen causing gray mold in over 200 plants species worldwide, including strawberry (Fragaria × ananassa). In Norway, gray mold is economically the most important ... -
Application of Bayesian calibration for propagation of uncertainty in dynamic models
(PhD Thesis;2010:8, Doctoral thesis, 2010)The thesis is about quantification of uncertainties in complex models. Models are built to describe, explain or predict a real world outcome. It is well known that models are related with uncertainty, and that uncertainties ... -
Applied and fundamental perspectives on brown-rot decay mechanisms
(PhD Thesis;2019:14, Doctoral thesis, 2019)Woody biomass is an important material for the growing bioeconomy, and has gained significant attention as a feedstock for second-generation biorefineries. Wood has traditionally been used as a building material for ... -
Back to basics : simplifying microbial communities to decrypt complex interactions
(PhD Thesis;2020:33, Doctoral thesis, 2020)Microbes are everywhere and contribute to many essential processes relevant for planet Earth, ranging from biogeochemical cycles to complex human behavior. The means to achieve these colossal tasks for such small and, at ... -
Bacteriocins : from discovery to characterization and applications
(PhD thesis;2023:74, Doctoral thesis, 2023)Multidrug resistant bacteria have become a major concern in both human and veterinary medicine. Due to the waning efficacy of many antibiotics, new antimicrobial agents are needed. Bacteriocins are ribosomally ... -
Better understanding of the relation of the dynamic sensory perception of solid and semi solid foods with consumers’ preferences and their perception of satiety
(PhD Thesis;2019:5, Doctoral thesis, 2019)Nowadays, overweight and obesity has been recognized as one of the main reasons that leads to many non-communicable diseases such as diabetes, high blood pressure, cardiovascular disease and in some cases cancer. Therefore, ... -
Biochemical investigation of catalysis by lytic polysaccharide monooxygenases
(PhD Thesis;2016:69, Doctoral thesis, 2018-05-04)Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that catalyze the oxidative cleavage of glycosidic bonds in the presence of dioxygen and an external electron donor. Currently, these enzymes are ... -
Biogas digestate as substrate and vector for the introduction of N2O-respiring bacteria to agricultural soil
(Phd Thesis;2021:53, Doctoral thesis, 2021)Anthropogenic nitrous oxide (N2O) emissions are largely driven by the input of N-based fertilizers in agriculture. N2O emissions from agricultural soils in Europe are estimated to 0.51 Tg annually (Fig. I), which sums to ... -
Cell-shape regulation in Streptococcus pneumoniae : EloR/KhpA, a new regulatory pathway administering cellelongation
(PhD Thesis;2020:36, Doctoral thesis, 2020)The oval shaped Streptococcus pneumoniae utilizes both septal and peripheral peptidoglycan (PG) synthesis in order to maintain its shape. The protein complexes responsible for synthesizing PG are called the elongasome and ... -
Characterization of fecal lactic acid bacteria isolated from healthy Ethiopian infants : bacteriocin production and antibiotic suscepebility
(PhD Thesis;2011:55, Doctoral thesis, 2011)In this thesis lactic acid bacteria (LAB) were isolated from fecal samples of healthy Ethiopian infants, identified to species level, screened for bacteriocin production and tested for antibiotic susceptibility. Enterococci ... -
Characterization of heteropathogenic and multidrugresistant (MDR) bacterial isolates from clinical and environmental sources using combined nanopore and next-generation sequencing technologies
(Doctoral thesis, 2020)Escherichia coli (E. coli) are usually harmless commensals that colonize the gastrointestinal tract of humans and other warm-blooded mammals. However, pathogenic counterparts have acquired virulence associated genes (VAGs) ... -
Characterization of the infant gut microbiota mobilome
(PhD thesis;2017:37, Doctoral thesis, 2017)The human gut is densely populated with a wide diversity of bacteria. These bacteria can serve as a reservoirs for multiple Antibiotic Resistance (AR) genes that in turn are associated with wide range of Mobile Genetic ... -
Cheese intake and risk factors for cardiovascular diseases and the metabolic syndrome : with particular reference to Gamalost intake and its effect on blood pressure
(PhD Thesis;2015:23, Doctoral thesis, 2020-11-10)The papers included in this thesis are part of a larger project titled “Healthy Cheese” (SUNN OST), with an overall main objective to establish a platform to develop innovative and healthy cheese varieties with reduced fat ... -
Cheese-making efficiency affected by protein source in concentrate feed for dairy cows and their αS1-κ-casein genotypes
(PhD Thesis;2023:32, Doctoral thesis, 2023)Evaluation of cheese-making efficiency is important for the dairy industry for profitability and sustainability reasons. Milk with a beneficial composition that favours good coagulation properties and a higher cheese yield ... -
Class II bacteriocins : target recognition, resistance and immunity
(PhD Thesis;2011:11, Doctoral thesis, 2011)Bacteriocins are bacterial antimicrobial peptides which are active against strains often closely related to the producer. Bacteriocins produced by food grade lactic acid bacteria are considered promising for applications ... -
Computational challenges in family genetics
(PhD Thesis;2015:36, Doctoral thesis, 2020-11-13)There is a constant demand to determine the most probable relationship between a set of person given some genetic marker data and some hypotheses about pedigree structure. A constant stream of paternity cases is obtained ...