Blar i Faculty of Chemistry, Biotechnology and Food Science (KBM) på tittel
Viser treff 317-336 av 1016
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Epigenetics : cell-type specific DNA methylation in the developing honey bee (Apis mellifera) brain
(Master thesis, 2014-07-28)DNA methylation is a prominent type of epigenetic modifications. Honey bees (Apis mellifera) serve as a model organism to study epigenetics as they have an epigenetic machinery homologous to mammals. However, the anatomical ... -
Establishment and characterization of a gatekeeper mutation for protein kinase D1 and 3
(Master thesis, 2016-09-07)Protein kinase D constitutes a novel family of Ser/Thr specific kinases and contains three members; PKD1-3. This protein kinase family has been described to carry out different functions and responses at various locations ... -
Establishment of a CD4+ naïve T cell cultivation and stimulation protocol for future studies of cellular responses in rheumatoid arthritis
(Master thesis, 2022)Rheumatoid arthritis (RA) is a complex autoimmune disease that primarily causes inflammation in the synovial membrane of joints in the body. It is a multifactorial disease that involves a combination of genetic, epigenetic, ... -
The establishment of a CRISPR-Cas13a diagnostic assay for SARS-CoV-2 detection
(Master thesis, 2020)The scarcity of fast and reliable tests in diagnostic laboratories for detection of pathogens with high sensitivity is a significant disadvantage particularly for critically ill patients. Given the global health crisis ... -
Establishment of gut microbiota in infants from a large Norwegian cohort
(PhD Thesis;2015:76, Doctoral thesis, 2020-11-10)Human gut microbiota, our so-called forgotten organ, is crucial for proper functioning of our body and for health maintenance. Although the topic of the gut microbiota establishment is very important, scientists still have ... -
Establishment of multiplexed reduced representation bisulfite sequencing protocol on T-cells from rheumatoid arthritis patients
(Master thesis, 2016-08-10)DNA methylation is an important epigenetic mark with a regulatory effect on the expression of genes. It has also been shown that individuals change their DNA methylation pattern over time. In mammals, methylation only ... -
Estimation of mixture-distributions using the Direct Look-up method
(Master thesis, 2012-10-16)Mixture distributions and models are useful methods of describing data that cannot be estimated with a single probability distribution. Estimating mixture models based on samples from unknown distributions is a highly ... -
Estimation of noise variance with dimension-reducing regression methods
(Master thesis, 2018)The focus of this thesis has been on investigating the performance of some estimators of the noise variance using the dimension-reducing methods PCR, PLSR and a recently developed Bayesian method, Bayes PLS, through a ... -
Estimation of small probabilities with applications to forensic genetics
(Master thesis, 2016-08-10)When determining kinship relations based on genetic material, there is a need to quantify the probability for doing errors. These probabilities are typically very small, but nonetheless important, and needs to be controlled. ... -
Etablering av gendeplesjonssystemet ComRS i et penicillinresistent klinisk isolat av Streptococcus pneumoniae for studier av resistensfaktorer
(Master thesis, 2023)Verdens helseorganisasjon erklærte Streptococcus pneumoniae (pneumokokker) som en av 12 prioriterte patogener. Både på grunnlag av dødeligheten og smittsomheten, men og på grunn av den økende forekomsten av antibiotikaresistens, ... -
Evaluating nuclear magnetic resonance (NMR) as a robust absolute reference method for water holding capacity (WHC) of pork meat
(PhD Thesis;2016:64, Doctoral thesis, 2017-01-05)Water holding capacity (WHC) is among the most important quality traits of meat. However, the mechanism behind WHC continues to be poorly understood and online measurement has yet to be achieved in the meat industry. The ... -
Evaluation and optimization of procedures for HPV detection and genotyping in oral and urine samples in men
(Master thesis, 2019)Human papillomavirus (HPV) has been well established as a carcinogen in human epithelial cancers; especially in the uterin cervix. Head and neck cancers (HNC) are increasing worldwide despite global reduction in smoking. ... -
Evaluation of GWAS Method Performance Focusing on Population Stratification and Cryptic Relatedness
(Master thesis, 2015-05-28)Genetic association studies are primarily used to identify genes associated with complex disease. It can be conducted by genotyping intentionally selected or randomly chosen markers. Numerous statistical and computational ... -
Evaluation of Liquid Array Diagnostics for microbiota-based diagnosis of dysbiosis
(Master thesis, 2018)The human gut contains a complex community of microorganisms that impact our health and general well-being. Based on observed microbial patterns, a balanced composition can be defined, known as normobiosis. Deviations from ... -
Evaluation of long-read Nanopore sequencing in genome studies
(Master thesis, 2017)The development of the latest generation of sequencing technologies, known as third-generation sequencing, has revolutionized sequence assembly due to long reads compared to the short reads of second-generation sequencing ... -
Evaluation of machine learning methods to decode transcriptional regulation
(Master thesis, 2023)With large biological measurements made possible by the development of high-throughput technology, it allows for the study of genomic data. In transcriptional regulation the cell controls the translation of DNA to RNA, and ... -
Evaluation of models for predicting the average monthly Euro versus Norwegian krone exchange rate from financial and commodity information
(Master thesis, 2015-05-12)Many multinational companies and policy makers carry out decisions by speculat- ing exchange rate. Exchange rate is determined by the demand and supply of a currency. It depends highly on variables like imports, exports, ... -
Evaluering av ATP overflatetester for påvisning av smuss og Listeria under forhold relevant for lakseindustri
(Master thesis, 2017)Det blir brukt mye ressurser på å overvåke renhold i prosessmiljøer for produksjon av lakseprodukter. Samtidig som dette er viktig for å sikre trygg mat med god kvalitet er det for industrien ønskelig å effektivisere ... -
Evaluering av metoder for isolering av DNA fra luftprøver og karakterisering av luftbårne bakterier i sykehusmiljø
(Master thesis, 2012-09-12) -
Evolution of alternative splice variation and exon usage following whole genome duplication
(Master thesis, 2022)Whole genome duplication and alternative splicing are two mechanisms that contribute to protein diversity. Whole genome duplication doubles the genetic material in an organism, providing raw material for adaptation and ...