dc.contributor.author | Hammerstad, Marta | |
dc.contributor.author | Kjendseth, Åsmund Røhr | |
dc.contributor.author | Hersleth, Hans-Petter | |
dc.date.accessioned | 2020-09-29T08:10:57Z | |
dc.date.available | 2020-09-29T08:10:57Z | |
dc.date.created | 2019-02-11T19:08:13Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Biochemistry and Molecular Biology Education. 2019, 47 (3), 318-332. | en_US |
dc.identifier.issn | 1470-8175 | |
dc.identifier.uri | https://hdl.handle.net/11250/2680146 | |
dc.description.abstract | Many laboratory courses consist of short and seemingly unconnected individual laboratory exercises. To increase the course consistency, relevance, and student engagement, we havedevelopedaresearch-inspiredandproject-basedmodule, “From Gene to Structure and Function”. This 2.5-week full-day biochemistry and structural biology module covers protein expression, purification, structure solving, and characterization.Themoduleiscenteredaroundthe flavodoxin-likeprotein NrdI, involved in the activation of the bacterial ribonucleotide reductase enzyme system. Through an in-depth focus on one specific protein, the students will learn the basic laboratory skills needed in order to generate a broader knowledge and breadth within the field. With respect to generic skills, the
studentsreporttheir findingsasascientificarticle,withtheaim to learn to present concise research results and write scientific papers. The current research-inspired project has the potential ofbeingfurtherdevelopedintoamorediscovery-drivenproject and extended to include other molecular biological techniques orbiochemical/biophysicalcharacterizations.Instudentevaluations, this research-inspired laboratory course has received very high ratings and been highly appreciated, where the students have gained research experience for more independent future work in the laboratory. © 2019 The Authors. Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry andMolecularBiology,47(3):318–332,2019. | en_US |
dc.language.iso | eng | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.subject | Læring og undervisning i høyere utdanning | en_US |
dc.subject | Teaching and learning in higher education | en_US |
dc.subject | Strukturbiologi | en_US |
dc.subject | Structural Biology | en_US |
dc.subject | Biokjemi | en_US |
dc.subject | Biochemistry | en_US |
dc.title | A Research-Inspired Biochemistry Laboratory Module - Combining Expression, Purification, Crystallization, Structure-Solving, and Characterization of a Flavodoxin-like Protein | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.subject.nsi | VDP::Kjemi: 440 | en_US |
dc.subject.nsi | VDP::Chemistry: 440 | en_US |
dc.source.pagenumber | 318-332 | en_US |
dc.source.volume | 47 | en_US |
dc.source.journal | Biochemistry and Molecular Biology Education | en_US |
dc.source.issue | 3 | en_US |
dc.identifier.doi | 10.1002/bmb.21218 | |
dc.identifier.cristin | 1676151 | |
dc.relation.project | Norges forskningsråd: 231669 | en_US |
cristin.unitcode | 192,12,0,0 | |
cristin.unitname | Kjemi, bioteknologi og matvitenskap | |
cristin.ispublished | true | |
cristin.qualitycode | 1 | |