Blar i Doctoral theses (VetMed) på utgivelsesdato
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Immunological and physiological effects of Piscine orthoreovirus infection in Atlantic salmon (Salmo salar)
(PhD Thesis;2017:33, Doctoral thesis, 2017)Heart and skeletal muscle inflammation (HSMI) is an important viral disease in Norwegian farmed Atlantic salmon (Salmo salar), and was associated with Piscine orthoreovirus (PRV) in 2010. Recently, the causality between ... -
Cocktails of persistent organic pollutants lead to behavioural and reproductive toxicity
(PhD thesis;2017:30, Doctoral thesis, 2017)Persistent organic pollutants (POPs) are chemicals that widely distributed in the environment and biota that could cause neurobehavioural and reproductive toxicity. As humans and animals are exposed to a complex mixture ... -
Infections associated with reproductive disorders in cattle in Tanzania : occurrence, characterization and impact
(PhD Thesis;2017:98, Doctoral thesis, 2017)The livestock sector in Tanzania is huge in animal numbers but the production is disproportionally small. Most of the infections known to cause reproductive disorders are generally regarded endemic in Africa, but more ... -
The cellular prion protein and the inflammatory response
(PhD Thesis;2017:81, Doctoral thesis, 2017)The cellular prion protein (PrPC) is known for its pivotal role in the development of prion diseases, such as Creutzfeldt-Jakob disease in humans and scrapie in small ruminants. In these diseases, PrPC is converted into a ... -
Effects of the rearing period and the production phase on fear-related responses in adult laying hens
(PhD Thesis;2017:48, Doctoral thesis, 2017)In 2013, almost seven billion laying hens (Gallus gallus domesticus) produced eggs for human consumption (CIWF, 2013). Under commercial egg production, specialised rearing farmers keep the birds until they are nearly ... -
Studies on the interbranchial lymphoid tissue in the gills of Atlantic salmon and common carp
(PhD Thesis;2017:17, Doctoral thesis, 2017)As wild-capture fisheries exceed sustainable levels, aquaculture is expected to increase its importance as a source of fish products for a growing world population. Vaccination is a major prophylactic measure in modern ... -
Influence of base-excision-repair pathway enzymes on prion pathogenesis
(PhD Thesis;2017:47, Doctoral thesis, 2017)Experimental prion disease in mice is a well-established model system for studying the pathogenesis of prion-induced neurodegeneration. The mouse-adapted Rocky Mountain Laboratories (RML) strain is commonly used for this ... -
Salmonid alphavirus infection in Atlantic salmon : viral properties and host responses to infection
(PhD Thesis;2015:2, Doctoral thesis, 2017-07-04)Pancreas disease (PD) is a contagious viral disease in salmonid aquaculture in Europe and North America. PD is caused by salmon pancreas disease virus also referred to as salmonid alphavirus (SAV), which belongs to the ... -
Investigation of the gut-associated lymphoid tissue in sheep with emphasis on natural killer cells
(PhD Thesis;2015:52, Doctoral thesis, 2017-07-04)The gut-associated lymphoid tissue (GALT) of sheep has been investigated for decades, and several immune cells receding within these structures have been described. The GALT of sheep has specialized compartments described ... -
Symmetrical onychomadesis and hypothyroidism in the Gordon Setter and English Setter
(PhD Thesis;2015:58, Doctoral thesis, 2017-07-04)Symmetrical onychomadesis (SO), also called symmetrical lupoid onychodystrophy, is a severe claw disease frequently seen in the Gordon Setter (GS) and English Setter (ES). Affected dogs will initially show sudden onset of ... -
Genetic studies of canine anxiety
(PhD Thesis;2016:51, Doctoral thesis, 2017-07-04)Canine anxiety is a common behavioral problem in dogs, affecting the dog’s welfare and health, and causing a strain in the relationship between the dog and its owner. Undesirable behaviors, including anxiety disorders, ... -
Studies of mechanisms of virulence of viral hemorrhagic septicemia (VHS) : comparison between different genotypes of the virus
(PhD Thesis;2015:17, Doctoral thesis, 2017-07-04)Viral hemorrhagic septicemia virus (VHSV) has four major genotypes (I, II, III, and IV) with different sub-lineages (Ia-e and IVa-c). VHSV infects a wide-host-range with a preference for low-temperature environments. The ... -
Characterization of salmonid alphavirus subtype 3 : recombination and adaptation
(PhD Thesis;2016:59, Doctoral thesis, 2017-07-04)Pancreas disease (PD) affecting Atlantic salmon (Salmo salar L.) and rainbow trout (Oncorhynchus mykiss) is a major burden in European salmonid aquaculture and causes major economical losses every year. The disease is ... -
Studies of oral vaccination against infectious pancreatic necrosis in Atlantic salmon : focus on antigen production, antigen kinetics, and immune responses
(PhD Thesis;2015:15, Doctoral thesis, 2017-07-04) -
Pathogenicity and infectivity of Saprolegnia species in Atlantic salmon (Salmo salar L.) and their eggs
(PhD Thesis;2015:97, Doctoral thesis, 2017-07-04)In the past decades the global population has becoming increasingly dependent on aquaculture due to over-fishing of oceans and rivers. Consequently, fish farming has become the fastest growing food sector in the world. ... -
Epidemiological, aetiological and prognostic aspects of canine primary bone cancer, with a view to its human counterpart
(PhD Thesis;2015:86, Doctoral thesis, 2017-07-05)Osteosarcoma (OSA) is the most common histological subtype of primary bone cancer in both humans and dogs. The importance of this relatively rare malignancy in humans is underlined by the fact that it typically affects ... -
Activation and recirculation of bovine natural killer cells in steady state and inflammation
(PhD Thesis;2015:40, Doctoral thesis, 2017-07-13)Natural killer (NK) cells are innate lymphocytes that act as early responders in the immune response by means of cytotoxicity and production of immunoregulatory cytokines. NK cells in cattle were described a decade ago, ... -
Monitoring of drug resistance and resistance development mechanisms in salmon lice (Lepeophtheirus salmonis)
(PhD Thesis;2015:44, Doctoral thesis, 2017-07-13)The parasite salmon louse (Lepeophtheirus salmonis) poses a threat to the salmonid aquaculture in the Northern Hemisphere. Depending on the developmental stage and the abundance of lice, these parasites can cause stress, ... -
Detection and quantification of the food-related bacterial toxins cereulide, lichenysin and botulinum neurotoxin/CD with liquid chromatography – tandem mass spectrometry
(PhD Thesis;2015:103, Doctoral thesis, 2017-07-13)Food‐ and waterborne illness has a tremendous impact on the society, both economically and through the vast number of diseased people. Increased focus on food safety both at the consumer level and in the food producing ... -
Microbial interactions : effects on virulence in Enterohaemorrhagic Escherichia coli (EHEC)
(PhD Thesis;2015:51, Doctoral thesis, 2017-07-13)Enterohaemorrhagic Escherichia coli (EHEC) is an emerging food borne pathogen associated with a number of outbreaks worldwide, and is a serious public health threat. The symptoms of the disease can range from mild diarrhoea ...