Blar i Doctoral theses (VetMed) på tittel
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Neurodevelopmental toxicity of a human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS)
(PhD Thesis;2021:63, Doctoral thesis, 2021)Persistent organic pollutants (POPs) are ubiquitous in the environment. Humans are continuously exposed to chemical mixtures through food and the environment. Exposure to POPs have been associated with several adverse ... -
Neuroendocrine regulation of pituitary gonadotropins during puberty in Atlantic salmon parr with focus on melatonin and Gnrh systems
(PhD Thesis;2018:105, Doctoral thesis, 2018)The pituitary gland, gonadotropins, together with neurohormones like gonadotropin-releasing hormone (Gnrh) and melatonin are key players in the control of vertebrate reproduction. In teleosts, despite the numerous studies ... -
New genomics and transcriptomics tools toward improving conservation strategies for sturgeons
(PhD Thesis;2020:12, Doctoral thesis, 2020)Sturgeons (Family Acipenseridae) are one of the largest and most primitive fish families on Earth. Although they have always been typically distributed throughout the Northern Hemisphere, during the last decades wild ... -
Noise reactivity and fear of fireworks in dogs : a study of genetic and phenotypic variables
(PhD Thesis;2023:1, Doctoral thesis, 2023)Noise reactivity is one of the most common behavioral problems in dogs. Even though various studies find significant differences in prevalence between breeds, and some also find gender differences, noise reactivity seems ... -
Non-neuronal functions of the prion protein : insights from a unique animal model
(PhD Thesis;2017:68, Doctoral thesis, 2017)The physiological function of the cellular prion protein (PrPC) remains enigmatic. A misfolded, infectious conformer of the protein, known as the scrapie isoform PrPSc, is able to aggregate in brain tissue and cause a group ... -
Non-typhoidal Salmonella in layer hen farms in Uganda : occurrence, biodiversity and antimicrobial resistance
(PhD Thesis;2018:83, Doctoral thesis, 2018)Non-typhoidal Salmonella (NTS) is an important global foodborne pathogen mainly acquired in humans from animal sources through consumption of contaminated animal products, contacts with animals or their environment, ... -
Nutrition and intestinal health in Atlantic salmon (Salmo salar) : involvement of antinutrients and microbiota
(PhD Thesis;2016:88, Doctoral thesis, 2016)The use of alternative protein ingredients to replace fishmeal in diets for Atlantic salmon (Salmo salar) can have negative consequences for the fish intestinal health. The most severe intestinal physiological and morphological ... -
Pathogenesis studies of cardiomyopathy syndrome (CMS) in Atlantic salmon, Salmo salar L.
(PhD Thesis;2021:78, Doctoral thesis, 2021)Cardiomyopathy syndrome (CMS) in farmed Atlantic salmon, Salmo salar L., is an infectious viral disease causing severe inflammation in the cardiac spongiosum of atrium and ventricle of the salmonid heart. The disease was ... -
Pathogenicity and infectivity of Saprolegnia species in Atlantic salmon (Salmo salar L.) and their eggs
(PhD Thesis;2015:97, Doctoral thesis, 2017-07-04)In the past decades the global population has becoming increasingly dependent on aquaculture due to over-fishing of oceans and rivers. Consequently, fish farming has become the fastest growing food sector in the world. ... -
Persistent infection of Piscine orthoreovirus-1 (PRV-1) in Atlantic salmon (Salmo salar)
(PhD thesis;2021:49, Doctoral thesis, 2021)This thesis focuses on infection kinetics, infected cell types, viral shedding, and specific immune responses in persistently Piscine orthoreovirus-1 (PRV-1) infected Atlantic salmon. The aim is to enhance the understanding ... -
Persistent Organic Pollutants (POPs) and heavy metals in fish from Tanzania : levels and associated health risks to humans and fish
(PhD Thesis;2019:17, Doctoral thesis, 2019)Diet is considered as the main route of exposure to pollutants such as persistent organic pollutants (POPs) and heavy metals to humans during lifetime. POPs and heavy metals are both persistent and can bioaccumulate in the ... -
Persistent organic pollutants and effects on developmental and functional processes in mice
(PhD Thesis;2020:45, Doctoral thesis, 2020)Initial exposure to persistent organic pollutants (POPs) occurs by placental and lactational transfer during fetal and neonatal life and continues during the adult stage through ingestion, inhalation and dermal absorption. ... -
Piecing together the chain of infection for Streptococcus dysgalactiae in sheep and dairy cows - risk factors, sources, and genomic diversity of bacterial strains
(PhD Thesis;2022:63, Doctoral thesis, 2022)Streptococcus dysgalactiae subspecies dysgalactiae (SDSD) is an important cause of outbreaks of infectious arthritis in lambs and mastitis in dairy cows in Norway. The infections compromise animal welfare, increase ... -
Plant-based aquafeeds : carry-over potential of mycotoxins and phytoestrogens from feed to fish and implication for fish health and food safety
(PhD Thesis;2020:62, Doctoral thesis, 2020)The introduction of novel feed ingredients has brought tremendous changes in the field of aquaculture. The shift to non-marine resources was necessary because of rising prices for fish meal and fish oil and their decreasing ... -
Porcine gut microbiota, short-chain fatty acids, and gut health in response to a high yeast inclusion diet
(PhD Thesis;2021:31, Doctoral thesis, 2021)The results of the PhD project have shown that high inclusion of Cyberlindnera jadinii yeast in pig feed exerts a prebiotic‑like effect. Beneficial intestinal lactic acid‑producing bacteria increase in numbers following ... -
The presence of an acute phase response in experimental classical scrapie in lambs indicates a shift towards a pro-inflammatory status in the clinical terminal stages
(PhD Thesis;2021:13, Doctoral thesis, 2020)Classical scrapie in sheep is a transmissible and fatal neurodegenerative disease caused by the self-replicating and infectious prion protein, PrPSc, which is a conformational variant of the normal cellular prion protein, ... -
Prevalence of anticoagulant rodenticides in dogs and red foxes
(PhD Thesis;2020:61, Doctoral thesis, 2021)Anticoagulant rodenticides (AR) are used worldwide in urban and agricultural rodent pest control. Ingestion of ARs is a major cause of poisoning in dogs and secondary exposure (ingestion of poisoned prey) in wildlife is a ... -
Prevalence, levels, risk factors and knowledge, attitudes and practices associated with mycotoxins in fish feeds and their effect in fish in Kenya
(PhD Thesis;2022:70, Doctoral thesis, 2022)Mycotoxins are low molecular weight chemical by-products of fungal metabolism. They are frequently detected in human foods and animal feeds in the tropics due to environmental conditions such as, warm and humid climate and ... -
Production of Atlantic salmon (Salmo salar) in closed confinement systems (CCS) : salmon lice, growth rates, mortality and fish welfare
(PhD Thesis;2019:48, Doctoral thesis, 2019)Farming of Atlantic salmon have been in rapid growth since the 1970's and is now an important industry in many countries around the North Atlantic as well as Chile. Since 2000, all countries with farming of Atlantic salmon ... -
Pulmonary micrometastasis and immunological pre-metastatic niche in dogs with osteosarcoma
(PhD Thesis;2023:49, Doctoral thesis, 2023)Cancer is currently ranked as a leading cause of death in humans and dogs, most often due to metastatic disease. The pre-metastatic niche (PMN) represents the metastasis-supporting microenvironmental changes that occur ...