Browsing Journal articles (peer reviewed) by Author "Dirven, Hubert"

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    • Exposure to human relevant mixtures of halogenated persistent organic pollutants (POPs) alters neurodevelopmental processes in human neural stem cells undergoing differentiation 

      Davidsen, Nichlas; Lauvås, Anna Jacobsen; Myhre, Oddvar; Ropstad, Erik; Carpi, Donatella; Mendoza-de Gyves, Emilio; Berntsen, Hanne Friis; Dirven, Hubert; Paulsen, Ragnhild Elisabeth; Bal-Price, Anna; Pistollato, Francesca (Peer reviewed; Journal article, 2021)
      Halogenated persistent organic pollutants (POPs) like perfluorinated alkylated substances (PFASs), brominated flame retardants (BFRs), organochlorine pesticides and polychlorinated biphenyls (PCBs) are known to cause cancer, ...

    • Exposure to persistent organic pollutants alters the serum metabolome in non-obese diabetic mice 

      Sinioja, Tim; Bodin, Johanna Eva; Duberg, Daniel; Dirven, Hubert; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Nygaard, Unni Cecilie; Orešič, Matej; Hyötyläinen, Tuulia (Peer reviewed; Journal article, 2022)
      Introduction Autoimmune disorders such as type 1 diabetes (T1D) are believed to be caused by the interplay between several genetic and environmental factors. Elucidation of the role of environmental factors in metabolic ...

    • New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project 

      Tal, Tamara; Myhre, Oddvar; Fritsche, Ellen; Rüegg, Joëlle; Craenen, Kai; Aiello-Holden, Kiara; Agrillo, Caroline; Babin, Patrick J.; Escher, Beate I.; Dirven, Hubert; Hellsten, Kati; Dolva, Kristine; Hessel, Ellen; Heusinkveld, Harm J.; Hadzhiev, Yavor; Hurem, Selma; Jagiello, Karolina; Judzinska, Beata; Klüver, Nils; Knoll-Gellida, Anja; Kühne, Britta A.; Leist, Marcel; Lislien, Malene; Lyche, Jan Ludvig; Müller, Ferenc; Colbourne, John K.; Neuhaus, Winfried; Pallocca, Giorgia; Seeger, Bettina; Scharkin, Ilka; Scholz, Stefan; Spjuth, Ola; Torres-Ruiz, Monica; Bartmann, Kristina (Peer reviewed; Journal article, 2024)

    • Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes 

      McGlinchey, Aidan; Sinioja, Tim; Lamichhane, Santosh; Sen, Partho; Bodin, Johanna Eva; Siljander, Heli; Dickens, Alex M.; Geng, Dawei; Carlsson, Cecilia; Duberg, Daniel; Ilonen, Jorma; Virtanen, Suvi M.; Dirven, Hubert; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Nygaard, Unni Cecilie; Orešič, Matej; Knip, Mikael; Hyötyläinen, Tuulia (Peer reviewed; Journal article, 2020)
      In the last decade, increasing incidence of type 1 diabetes (T1D) stabilized in Finland, a phenomenon that coincides with tighter regulation of perfluoroalkyl substances (PFAS). Here, we quantified PFAS to examine their ...