Viser treff 501-520 av 1051
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A new method for the synthesis of fatty acid amides
(Master thesis, 2018)The amide bond is an essential part of many natural products and is also found in a lot of today’s pharmaceuticals. The fatty acid amides are a group of natural products that has shown biological activity towards several ... -
Screening for antimicrobial agents against the fish pathogens, Streptococcus agalactiae and Yersinia ruckeri, in fermented fruit and vegetables
(Master thesis, 2018)Antibiotics have been used for a long period of time both for human and animal health, as well as economical benefits. Because of an emerging antibiotic resistance in pathogen microbes, there is an increasing need for new ... -
Immunotherapeutic targeting of tumor-associated macrophages
(Master thesis, 2018)The development of CAR T cell technology allows for MHC-independent recognition of a native target antigen by T cells. In august 2017, the first CD19-specific CAR T cell therapy was approved in the U.S. for the treatment ... -
Kjøkkenvaner og mattrygghet hos forbrukeren : fokus på krysskontaminering og hygiene etter håndtering av rå kylling
(Master thesis, 2018)Matbåren sykdom er et helsemessig og samfunnsøkonomisk problem. For å sikre trygg mat til alle, er det utformet en strategi som skal dekke hele matkjeden fra «jord/fjord til bord». Det er derimot vanskelig å kontrollere ... -
Identification of celiac disease related immunogenic peptides in Norwegian wheat types after ex vivo digestion
(Master thesis, 2018)Wheat has been part of human diet for centuries in the form of bread, pasta, cakes and pastries. There has been a lot of research to introduce better crop yield and disease resistant wheat varieties. Today’s wheat varieties ... -
On the application of machine learning techniques for phenotypic classification and clustering of heart failure patients
(Master thesis, 2018)In this thesis, we attempt to investigate how well various clustering algorithms (hierarchical clustering, k-means and expectation–maximization) perform in producing phenotypically distinct clinical patient groups (i.e. ... -
Evaluation of Liquid Array Diagnostics for microbiota-based diagnosis of dysbiosis
(Master thesis, 2018)The human gut contains a complex community of microorganisms that impact our health and general well-being. Based on observed microbial patterns, a balanced composition can be defined, known as normobiosis. Deviations from ... -
The first stereoselective syntheses of (all-Z)- hentriaconta-3,6,9,12,15,19,22,25,28-nonaene and obscuraminol A, two polyunsaturated natural products
(PhD Thesis;2015:75, Doctoral thesis, 2018-12-19)The research described herein focuses on stereoselective synthesis of some Z-polyenoic natural products, making them available for biological studies. The objectives of the study can be subdivided into three parts integrated ... -
Characterization of Lactic Acid Bacteria from infants gut with antimicrobial activity against Lactobacillus rhamnosus GG
(Master thesis, 2018)There are major individual differences in how the probiotic strain Lactobacillus rhamnosus GG (LGG) colonizes the intestine of infants. Understanding these differences will be of great importance in relation to the use of ... -
Improving food waste anaerobic digestion : effects of digestate recirculation, post-treatment and methane-methane serial digestion
(PhD Thesis;2018:53, Doctoral thesis, 2018)Anaerobic digestion of food waste generates two valuable products: digestate and biogas. Today, most food waste in Norway is incinerated because it is collected as mixed waste. Hence, a shift from incineration to anaerobic ... -
Development of an optimized gas chromatography / triple quadrupole mass spectrometry method for the quantitative determination of nitro- and oxygen containing polycyclic aromatic hydrocarbons (N-/ O-PAHs) in atmospheric samples
(Master thesis, 2018)Nitrated and oxygenated polycyclic aromatic hydrocarbons (nitro-/oxy-PAHs) are organic pollutants which are released to the atmosphere from incomplete combustion processes, or formed by degradation of their parent PAH ... -
The effects of eggshell membrane on muscle formation in 2D and 3D environments
(Master thesis, 2018)A shortage of available tissues and organs for transplantation has led to suffering and death for many people. Tissue engineering could be a possible solution to this shortage, and the most common approach is to use a ... -
Genotypic and phenotypic antimicrobial resistance in the opportunistic pathogen Stenotrophomonas maltophilia
(Master thesis, 2018)Stenotrophomonas maltophilia er hovedsakelig kjent som en miljøbakterie, men innehar også den egenskapen å være opportunistisk patogen. Hos pasienter er bakterien ofte assosiert med kolonisering, men kan sporadisk skape ... -
Proteolyse ved eksogene enzymer gir mulige effekter på spisekvalitet, proteinfordøyelse og bioaktivitet i Semitendinosus
(Master thesis, 2018)Mørhet er avgjørende når forbruker velger kjøttstykke. I framtidens kjøttproduksjon kan tilførsel av eksogene enzymer muligens bidra til forbedret mørhet i seige muskler som normalt brukes til prosessert kjøtt. Videre kan ... -
The host DNA challenge in the analysis of microbiota from Atlantic salmon (Salmo salar)
(Master thesis, 2018)DNA contamination is a challenge in the modern age of new generation sequencing. Contaminants lead to misassembly, wrongful associations and a decrease in cost efficiency of sequencing. The same is true for host DNA ... -
Syntese av 5-((3-hydroksy-1-(4-hydroksy-3,5-dimetoksyfenyl)-2-(2-metoksyfenoksy)propoksy)metyl)furan-2-karbaldehyd og undersøkelse av mulige endringer av lignin etter dampeksplosjon
(Master thesis, 2018)Målet med oppgaven var å syntetisere trimeren 5-((3-hydroksy-1-(4-hydroksy-3,5-dimetoksyfenyl)-2-(2-metoksyfenoksy)propoksy)metyl)furan-2-karbaldehyd (14). Denne trimeren er et mulig biprodukt av dampeksplosjon hvor ett ... -
Rollen til det ROS-genererende enzymet NADPH oksidase 1 ved lavgrads inflammasjon i tykktarm
(Master thesis, 2018)Bakgrunn: I kroppen dannes reaktive oksygenforbindelser (ROS) i så godt som alle typer celler og vev, hvor de utfører mange ulike og viktige funksjoner. I denne sammenheng ansees enzymer kalt NADPH oksidaser (NOX-enzymer) ... -
Uttrykk og karakterisering av en superoksid dismutase og en dihyrolipoamid dehydrogenase fra Thermobifida fusca
(Master thesis, 2018)Denne oppgaven er skrevet som en del av et større forskningsprosjekt med et overordnende mål om å tilegne seg kunnskap om ligninnedbrytende enzymer til jordbakterien Thermobifidia fusca. Lignocellulose består hovedsakelig ... -
Analytical challenges in the determination of legacy and novel brominated flame retardants : a method development study
(Master thesis, 2018)Legacy brominated flame-retardants (BFRs) such as polybrominated diphenyl ethers (PBDE) have been widely used in technical flame-retardant mixtures, as they inhibit the combustion processes and secures fire resistance in ... -
Bacillus weihenstephanensis samkulturert med Pseudomonas spp. og Paenibacillus lactis i kjølelagret melk : vekst og produksjon av kvalitetsforringende komponenter
(Master thesis, 2018)Sammensetningen av den psykotrofe bakteriefloraen i melk endres over tid og påvirkes blant annet av årstid, kjøletemperatur og tidspunkt i holdbarhetsperioden. Hensikten med denne oppgaven var å undersøke hvordan Bacillus ...