Blar i Faculty of Chemistry, Biotechnology and Food Science (KBM) på forfatter "Sandve, Simen Rød"
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Deciphering transcriptional regulation using deep neural networks
Førrisdal, Julie Wollebæk (Master thesis, 2023)The DNA holds the recipe of all life functions. To decipher the instructions, one has to learn and understand its complex syntax. The non-coding DNA contains regulatory elements, that are essential to control and activate ... -
The establishment of a CRISPR-Cas13a diagnostic assay for SARS-CoV-2 detection
Krog, Charlotte Solum (Master thesis, 2020)The scarcity of fast and reliable tests in diagnostic laboratories for detection of pathogens with high sensitivity is a significant disadvantage particularly for critically ill patients. Given the global health crisis ... -
Evaluation of machine learning methods to decode transcriptional regulation
Jeyakumar, Harini (Master thesis, 2023)With large biological measurements made possible by the development of high-throughput technology, it allows for the study of genomic data. In transcriptional regulation the cell controls the translation of DNA to RNA, and ... -
Evolution of alternative splice variation and exon usage following whole genome duplication
Sandholm, Ronja Marlonsdotter (Master thesis, 2022)Whole genome duplication and alternative splicing are two mechanisms that contribute to protein diversity. Whole genome duplication doubles the genetic material in an organism, providing raw material for adaptation and ... -
Evolution of gene expression following the whole genome duplication in salmonid fish
Gillard, Gareth Benjamin (PhD Thesis;2019:53, Doctoral thesis, 2019)Whole genome duplication (WGD) is a rare mutational event that provides additional duplicates of all genes in the entire genome, resulting in functional redundancy. This redundancy leads to relaxation of selective constraints ... -
Exploring host-microbiome interactions in Norwegian Salmon via weighted network analysis
Strand, Marius André (Master thesis, 2019)Invisible to the naked eye, but present everywhere. Microbial organisms live and reproduce in almost any conceivable environment on the planet. In recent years, researchers have started to gain quantified information of ... -
Homeolog regulation in hexaploid wheat
Hallsberg, Ine Birgitta (Master thesis, 2016-09-15)Bread wheat (Triticum aestivum L.) is an allohexaploid hybrid composed of three closely related diploid subgenomes (AABBDD, 2n=6x=42). For most genes, bread wheat therefore has three gene copies, referred to as homeolog ... -
Optimization of transfection of primary hepatocytes from Atlantic salmon for functional studies
Wilberg, Ragnhild (Master thesis, 2020)Gene expression in eukaryotes are regulated through complex interactions between regulatory proteins, cis-regulatory sequences as well as chemical modifications and structure of chromatin. The function of cis-regulatory ...