Blar i Faculty of Chemistry, Biotechnology and Food Science (KBM) på forfatter "Carlsen, Harald"
-
Pharmacological tools to study transcriptional addictions in cancer
Iliev, Hristo Kostadinov (Master thesis, 2022)Unfortunately, genetic diseases such as cancer are becoming more common among the global popu-lation, and only in 2020 approximately 19 million new cases were discovered, and 10 million lives were lost. With median overall ... -
The role of coagulation factor V in breast cancer : effect on treatment response
Lind, Sara Marie (Master thesis, 2021)Sammenhengen mellom kreft og koagulasjon er vel etablert og det er kjent at kreftpasienter har en økt risiko for å utvikle trombose. Kreftceller kan ofte uttrykke koagulasjonsfaktorer som fører til ubalanse i hemostasen ... -
The role of HCAR1 on oligodendrocyte proliferation and survival after neonatal hypoxia ischemia in mice
Austbø, Marie Landa (Master thesis, 2021)Neonatal cerebral hypoxia-ischemia (HI) is a leading cause of death and disability in infants. It is characterized by insufficient supply of blood and oxygen to the brain, resulting in cell death and tissue loss. The only ... -
Rollen til det ROS-genererende enzymet NADPH oksidase 1 ved lavgrads inflammasjon i tykktarm
Herfindal, Anne Mari (Master thesis, 2018)Bakgrunn: I kroppen dannes reaktive oksygenforbindelser (ROS) i så godt som alle typer celler og vev, hvor de utfører mange ulike og viktige funksjoner. I denne sammenheng ansees enzymer kalt NADPH oksidaser (NOX-enzymer) ... -
Single-cell analysis of ER-positive breast cancer treated with letrozole and ribociclib
Vander-Elst, Karoline Rapp (Master thesis, 2022)Breast cancer is the most widespread cancer in the world, accounting for 25% of all female cancers. There is a high inter- and intra-tumor heterogeneity in breast cancer which makes it challenging to optimize the treatment ... -
Small intestinal microbiota – Regulation by reactive oxygen species and influence of diet
Kielland, Chrysoula (PhD Thesis;2022:5, Doctoral thesis, 2022)Over the last years multiple studies have analyzed the impact of intestinal microbiota on health. Certain changes in the composition of the microbial population in the intestine have been associated with several diseases ... -
Systematic evaluation of RT-qPCR kits and protocols for detection and quantitation of microRNAs
Andersen, Sofie Strøm (Master thesis, 2019)MicroRNAs (miRNAs) are small single-stranded non-coding RNAs with an average length of ~ 22 nucleotides. The main function of miRNA is post-transcriptional regulation of gene expression by targeting specific mRNAs. The ... -
The functional role of coagulation factor V in liver cancer
McCoig, Cathrine (Master thesis, 2018)Sammenhengen mellom koagulasjon og kreft er velkjent. Kreftpasienter har en dokumentert økt risiko for trombose, og kreftceller kan også frigi kreft-prokoagulanter og mikropartikler som direkte aktiverer koagulasjonssystemet. ... -
The role of coagulation factor V in breast cancer
Fredhjem, Marianne Staff (Master thesis, 2018)Pasienter med kreftsykdommer har en økt risiko for thromboemboliske sykdommer, og det er også etablert en sammenheng mellom koagulasjons faktorer og økt risiko for tumor progresjon. En bedre forståelse av de underliggende ... -
The role of the rseP gene in systemic infection of mice
Djuvik, Ingve Gudvin Røv (Master thesis, 2019)The group of antimicrobial substances collectively known as antibiotics is humanity's foremost weapon against a range of pathogenic bacteria but is also getting increasingly compromised with the rise of antibiotic resistance. ... -
Time restricted eating and effects on metabolic syndrome and health markers for metabolic syndrome : a systematic review of human clinical trials
Bjerke, Helene Halsnes (Master thesis, 2023)Metabolic syndrome (MetS) is a cluster of risk factors that significantly increase the likelihood of developing chronic health conditions such as cardiovascular disease, type 2 diabetes mellitus, and non-alcoholic fatty ... -
Transcriptomic analysis of pancreatic islet cells derived from stem cells
Abrahamsen, Martine (Master thesis, 2020)Diabetes mellitus type 1 is an autoimmune disease leading to the destruction of the pancreatic beta-cells. The beta-cells are responsible for secreting the hormone insulin which lowers the blood sugar after a meal. Dysfunction ...