Blar i Brage NMBU på forfatter "Alestrøm, Peter"
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Altered non-coding RNA expression profile in F1 progeny 1 year after parental irradiation is linked to adverse effects in zebrafish
Martin, Leonardo M; Kamstra, Jorke; Hurem, Selma; Lindeman, Leif Christopher; Brede, Dag Anders; Aanes, Håvard; Babiak, Igor; Arenal, Amilcar; Oughton, Deborah H; Salbu, Brit; Lyche, Jan Ludvig; Alestrøm, Peter (Peer reviewed; Journal article, 2021)Gamma radiation produces DNA instability and impaired phenotype. Previously, we observed negative effects on phenotype, DNA methylation, and gene expression profiles, in offspring of zebrafish exposed to gamma radiation ... -
Differential DNA methylation at conserved non‑genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2‑ethylhexyl) phthalate and 5‑azacytidine in zebrafish
Kamstra, Jorke Harmen; Sales, Liana Bastos; Alestrøm, Peter; Legler, Juliette (Journal article; Peer reviewed, 2017) -
Effects of microgravity simulation on zebrafish transcriptomes and bone physiology—exposure starting at 5 days post fertilization
van Loon, Jack J.W.A.; Maier, Jeanette A.; Nourizadeh-Lillabadi, Rasoul; Aceto, Jessica; Bradamante, Silvia; Alestrøm, Peter (Journal article; Peer reviewed, 2016) -
Epigenetic, transcriptional and phenotypic responses in two generations of Daphnia magna exposed to the DNA methylation inhibitor 5-Azacytidine
Lindeman, Leif Christopher; Thaulow, Jens; Song, You; Kamstra, Jorke H; Xie, Li; Asselman, Jana; Alestrøm, Peter; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2019)The water flea Daphnia magna is a keystone species in freshwater ecosystems and has been widely used as a model organism in environmental ecotoxicology. This aquatic crustacean is sensitive to environmental stressors and ... -
Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
Hurem, Selma; Gomes, Tania; Brede, Dag Anders; Mayer, Ian; Lobert, Viola; Mutoloki, Stephen; Gutzkow, Kristine Bjerve; Teien, Hans-Christian; Oughton, Deborah Helen; Alestrøm, Peter; Lyche, Jan Ludvig (Journal article; Peer reviewed, 2018)The biological effects of gamma radiation may exert damage beyond that of the individual through its deleterious effects on reproductive function. Impaired reproductive performance can result in reduced population size ... -
Gamma radiation induces locus specific changes to histone modification enrichment in zebrafish and Atlantic salmon
Lindeman, Leif Christopher; Kamstra, Jorke; Ballangby, Jarle; Hurem, Selma; Martin, Leonardo M; Brede, Dag Anders; Teien, Hans-Christian; Oughton, Deborah H; Salbu, Brit; Lyche, Jan Ludvig; Alestrøm, Peter (Journal article; Peer reviewed, 2019)Ionizing radiation is a recognized genotoxic agent, however, little is known about the role of the functional form of DNA in these processes. Post translational modifications on histone proteins control the organization ... -
Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish
den Broeder, Marjo J.; Ballangby, Jarle; Kamminga, Leonie M.; Alestrøm, Peter; Legler, Juliette; Lindeman, Leif Christopher; Kamstra, Jorke Harmen (Peer reviewed; Journal article, 2020) -
Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish
Kamstra, Jorke Harmen; Hurem, Selma; Martin, Leonardo M; Lindeman, Leif Christopher; Legler, Juliette; Oughton, Deborah H.; Salbu, Brit; Brede, Dag Anders; Lyche, Jan Ludvig; Alestrøm, Peter (Journal article; Peer reviewed, 2018) -
Two-generational study of biological effects from gamma radiation exposure during sensitive life stages in the zebrafish (Danio rerio)
Hurem, Selma (PhD Thesis;2018:11, Doctoral thesis, 2018)There is growing concern about the harmful effects of ionizing radiation on animal populations, including potential effects on future generations. A number of life stages are particularly sensitive to radiation exposure ... -
Zebrafish bone and general physiology are differently affected by hormones or changes in gravity
Aceto, Jessica; Nourizadeh-Lillabadi, Rasoul; Maree, Raphael; Dardenne, Nadia; Jeanray, Nathalie; Wehenkel, Louis; Alestrøm, Peter; van Loon, Jack J.W.A.; Muller, Marc (Journal article; Peer reviewed, 2015) -
Zebrafish: Housing and husbandry recommendations
Alestrøm, Peter; D'Angelo, Livia; Midtlyng, Paul; Schorderet, Daniel F; Schulte-Merker, Stefan; Sohm, Frederic; Warner, Susan (Peer reviewed; Journal article, 2019)This article provides recommendations for the care of laboratory zebrafish (Danio rerio) as part of the further implementation of Annex A to the European Convention on the protection of vertebrate animals used for experimental ...