Vis enkel innførsel

dc.contributor.authorCiani, Elia
dc.contributor.authorHaug, Trude M
dc.contributor.authorMaugars, Gersende Marie Aimee
dc.contributor.authorWeltzien, Finn-Arne
dc.contributor.authorFalcón, Jack
dc.contributor.authorFontaine, Romain
dc.date.accessioned2021-09-16T11:26:41Z
dc.date.available2021-09-16T11:26:41Z
dc.date.created2021-01-11T18:27:17Z
dc.date.issued2021
dc.identifier.citationFrontiers in Endocrinology. 2021, 11 1-20.
dc.identifier.issn1664-2392
dc.identifier.urihttps://hdl.handle.net/11250/2778596
dc.description.abstractMelatonin is a key hormone involved in the photoperiodic signaling pathway. In both teleosts and mammals, melatonin produced in the pineal gland at night is released into the blood and cerebrospinal fluid, providing rhythmic information to the whole organism. Melatonin acts via specific receptors, allowing the synchronization of daily and annual physiological rhythms to environmental conditions. The pituitary gland, which produces several hormones involved in a variety of physiological processes such as growth, metabolism, stress and reproduction, is an important target of melatonin. Melatonin modulates pituitary cellular activities, adjusting the synthesis and release of the different pituitary hormones to the functional demands, which changes during the day, seasons and life stages. It is, however, not always clear whether melatonin acts directly or indirectly on the pituitary. Indeed, melatonin also acts both upstream, on brain centers that control the pituitary hormone production and release, as well as downstream, on the tissues targeted by the pituitary hormones, which provide positive and negative feedback to the pituitary gland. In this review, we describe the known pathways through which melatonin modulates anterior pituitary hormonal production, distinguishing indirect effects mediated by brain centers from direct effects on the anterior pituitary. We also highlight similarities and differences between teleosts and mammals, drawing attention to knowledge gaps, and suggesting aims for future research.
dc.language.isoeng
dc.titleEffects of Melatonin on Anterior Pituitary Plasticity: A Comparison Between Mammals and Teleosts
dc.typePeer reviewed
dc.typeJournal article
dc.description.versionpublishedVersion
dc.source.pagenumber1-20
dc.source.volume11
dc.source.journalFrontiers in Endocrinology
dc.identifier.doi10.3389/fendo.2020.605111
dc.identifier.cristin1869354
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel