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dc.contributor.authorPaulsen, Katrine Mørk
dc.contributor.authorDas Neves, Carlos G
dc.contributor.authorGranquist, Erik Georg
dc.contributor.authorMadslien, Knut Ivar Engesæter
dc.contributor.authorStuen, Snorre
dc.contributor.authorPedersen, Benedikte Nevjen
dc.contributor.authorVikse, Rose
dc.contributor.authorRocchi, Mara
dc.contributor.authorLaming, Eleanor
dc.contributor.authorStiasny, Karin
dc.contributor.authorAndreassen, Åshild Kristine
dc.date.accessioned2020-08-03T07:32:57Z
dc.date.available2020-08-03T07:32:57Z
dc.date.created2020-01-13T15:10:08Z
dc.date.issued2019
dc.identifier.citationZoonoses and Public Health. 2019, .en_US
dc.identifier.issn1863-1959
dc.identifier.urihttps://hdl.handle.net/11250/2670599
dc.description.abstractTick‐borne encephalitis virus (TBEV) is the causative agent of tick‐borne encephalitis (TBE). TBEV is one of the most important neurological pathogens transmitted by tick bites in Europe. The objectives of this study were to investigate the seroprevalence of TBE antibodies in cervids in Norway and the possible emergence of new foci, and furthermore to evaluate if cervids can function as sentinel animals for the distribution of TBEV in the country. Serum samples from 286 moose, 148 roe deer, 140 red deer and 83 reindeer from all over Norway were collected and screened for TBE immunoglobulin G (IgG) antibodies with a modified commercial enzyme‐linked immunosorbent assay (ELISA) and confirmed by TBEV serum neutralisation test (SNT). The overall seroprevalence against the TBEV complex in the cervid specimens from Norway was 4.6%. The highest number of seropositive cervids was found in south‐eastern Norway, but seropositive cervids were also detected in southern‐ and central Norway. Antibodies against TBEV detected by SNT were present in 9.4% of the moose samples, 1.4% in red deer, 0.7% in roe deer, and nil in reindeer. The majority of the positive samples in our study originated from areas where human cases of TBE have been reported in Norway. The study is the first comprehensive screening of cervid species in Norway for antibodies to TBEV, and shows that cervids are useful sentinel animals to indicate TBEV occurrence, as supplement to studies in ticks. Furthermore, the results indicate that TBEV might be spreading northwards in Norway. This information may be of relevance for public health considerations and supports previous findings of TBEV in ticks in Norway.en_US
dc.language.isoengen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleCervids as sentinel-species for tick-borne encephalitis virus in Norway - A serological studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber10en_US
dc.source.volume67en_US
dc.source.journalZoonoses and Public Healthen_US
dc.source.issue4en_US
dc.identifier.doi10.1111/zph.12675
dc.identifier.cristin1771672
dc.relation.projectInterreg: 167226en_US
dc.relation.projectInterreg: 20200422en_US
dc.relation.projectHelsedepartementet: B1412en_US
cristin.unitcode192,16,3,0
cristin.unitnameInstitutt for produksjonsdyrmedisin
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


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