Developing of a SNP based parentage testing panel in the Norwegian goat
Master thesis
Permanent lenke
http://hdl.handle.net/11250/2359442Utgivelsesdato
2015-11-05Metadata
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- Master's theses (IHA) [318]
Sammendrag
A parentage test for Norwegian goats consisting of 59 highly informative SNPs has
been developed. A panel of 48 AI bucks genotyped by the Illumina 50K SNP chip were used to select 80 highly informative SNPs for the parentage test. The 80 SNP parentage panel was evaluated by genotyping the 48 AI bucks together with 143 potential breeding bucks. According to the pedigree, 121 of the 143 potential breeding bucks were sired by one of the 48 AI bucks, allowing for parentage testing by the SNP-panel. The SNP based parentage analysis showed that 15% of the parentages were most likely wrongly assigned. Theoretical considerations show that the panel had a high power of non-exclusion (EPN= 0.004), given a MAF of 0.44 and only a single parent genotyped. We therefore conclude that this 59 based parentage SNP panel is an effective tool for excluding incorrect assigned sires in the Norwegian breeding system.