Browsing Brage NMBU by Author "Weltzien, Finn-Arne"
Now showing items 1-20 of 33
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3D Atlas of the Pituitary Gland of the Model Fish Medaka (Oryzias latipes)
Royan, Muhammad Rahmad; Siddique, Khadeeja; Csucs, Gergely; Puchades, Maja; Nourizadeh-Lillabadi, Rasoul; Bjaalie, Jan G.; Henkel, Christiaan; Weltzien, Finn-Arne; Fontaine, Romain (Peer reviewed; Journal article, 2021)In vertebrates, the anterior pituitary plays a crucial role in regulating several essential physiological processes via the secretion of at least seven peptide hormones by different endocrine cell types. Comparative and ... -
A computational model for gonadotropin releasing cells in the teleost fish medaka
Halnes, Geir; Tennøe, Simen; Haug, Trude; Einevoll, Gaute; Weltzien, Finn-Arne; Hodne, Kjetil (Journal article; Peer reviewed, 2019)Pituitary endocrine cells fire action potentials (APs) to regulate their cytosolic Ca2+ concentration and hormone secretion rate. Depending on animal species, cell type, and biological conditions, pituitary APs are generated ... -
An Atlantic cod (Gadus morhua L.) pituitary model system for reproductive and reprotoxic testing in vitro
von Krogh, Kristine (PhD Thesis;2021:14, Doctoral thesis, 2021)Due to factors such as overfishing, climate changes and pollution, most fish stocks are in decline. This is also the case for the commercially important marine species, Atlantic cod (Gadus morhua). As a result, the last ... -
Brain-infecting parasites leave lasting effects on behaviour even in resistant hosts
Vindas, Marco; Midttun, Helene Louise Eghave; Nadler, Lauren Elizabeth; Fontaine, Romain; Weltzien, Finn-Arne; Øverli, Øyvind; Johansen, Ida Beitnes (Peer reviewed; Journal article, 2022) -
Characterization of gonadotropin receptors Fshr and Lhr in Japanese medaka, Oryzias latipes
Burow, Susann; Mizrahi, Naama; Maugars, Gersende Marie Aimee; von Krogh, Kristine; Nourizadeh-Lillabadi, Rasoul; Hollander-Cohen, Lian; Shpilman, Michal; Atre, Ishwar; Weltzien, Finn-Arne; Levavi-Sivan, Berta (Peer reviewed; Journal article, 2020)Reproduction in vertebrates is controlled by the brain-pituitary-gonad axis, where the two gonadotropins follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh) play vital parts by activating their cognate receptors ... -
Characterization of teleost pituitary cell types using single-cell transcriptomics (scRNA-seq)
Siddique, Khadeeja (PhD Thesis;2022:20, Doctoral thesis, 2022)The pituitary gland is an endocrine gland found in vertebrates. It produces and secretes a variety of essential peptide hormones which regulate several physiological functions, such as reproduction, growth, metabolism, ... -
Cold seawater induces early sexual developmental stages in the BPG axis of European eel males
Rozenfeld, Christoffer; García-Carpintero, Victor; Pérez, Luz; Gallego, Victor; Herranz-Jusdado, Juan Germán; Tveiten, Helge; Johnsen, Helge K.; Fontaine, Romain David; Weltzien, Finn-Arne; Cañizares, Joaquín; Asturiano, Juan F.; Penaranda, David Sanchez (Journal article; Peer reviewed, 2019) -
Cortisol differentially affects cell viability and reproduction-related gene expression in Atlantic cod pituitary cultures dependent on stage of sexual maturation
von Krogh, Kristine; Bjørndal, Gunnveig Toft; Nourizadeh-Lillabadi, Rasoul; Ropstad, Erik; Haug, Trude; Weltzien, Finn-Arne (Journal article; Peer reviewed, 2019)Through the action of cortisol, stress can affect reproductive biology with behavioural and physiological alterations. Using mixed sex primary pituitary cultures from Atlantic cod (Gadus morhua), the present study aimed ... -
Data on Western blot and ELISA analysis of medaka (Oryzias latipes) follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh) using recombinant proteins expressed with Pichia pastoris
Burow, Susann; Fontaine, Romain; von Krogh, Kristine; Mayer, Ian; Nourizadeh-Lillabadi, Rasoul; Hollander-Cohen, Lian; Cohen, Yaron; Shpilman, Michal; Levavi-Sivan, Berta; Weltzien, Finn-Arne (Journal article; Peer reviewed, 2019)The gonadotropins follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh) play essential roles in vertebrate reproduction. This article presents data on molecular weight validation of recombinant medaka (Oryzias ... -
Direct and indirect effects of sex steroids on gonadotrope cell plasticity in the teleost fish pituitary
Fontaine, Romain; Royan, Muhammad Rahmad; von Krogh, Kristine; Weltzien, Finn-Arne; Baker, Dianne (Peer reviewed; Journal article, 2020) -
Effects of Melatonin on Anterior Pituitary Plasticity: A Comparison Between Mammals and Teleosts
Ciani, Elia; Haug, Trude M; Maugars, Gersende Marie Aimee; Weltzien, Finn-Arne; Falcón, Jack; Fontaine, Romain (Peer reviewed; Journal article, 2021)Melatonin is a key hormone involved in the photoperiodic signaling pathway. In both teleosts and mammals, melatonin produced in the pineal gland at night is released into the blood and cerebrospinal fluid, providing rhythmic ... -
Establishment of specific enzyme-linked immunosorbent assay (ELISA) for measuring Fsh and Lh levels in medaka (Oryzias latipes), using recombinant gonadotropins
Burow, Susann; Fontaine, Romain David; von Krogh, Kristine; Mayer, Ian; Nourizadeh-Lillabadi, Rasoul; Hollander-Cohen, Lian; Cohen, Yaron; Shpilman, Michal; Levavi-Sivan, Berta; Weltzien, Finn-Arne (Journal article; Peer reviewed, 2019)The paucity of information on understanding the regulatory mechanisms that are involved in the control of piscine Fsh and Lh synthesis, secretion, and function, prompted the present work. Part of the problem is related to ... -
Functional divergence of thyrotropin beta-subunit paralogs gives new insights into salmon smoltification metamorphosis
Fleming, Mitchell S.; Maugars, Gersende Marie Aimee; Lafont, Anne-Gaëlle; Rancon, Jocelyn; Fontaine, Romain; Nourizadeh-Lillabadi, Rasoul; Weltzien, Finn-Arne; Yebra-Pimente, Elena Santidrian; Dirks, Ron; McCormick, Stephen D.; Rousseau, Karine; Martin, Patrick; Dufour, Sylvie (Journal article; Peer reviewed, 2019)Smoltification is a metamorphic event in salmon life history, which initiates downstream migration and pre-adapts juvenile salmon for seawater entry. While a number of reports concern thyroid hormones and smoltification, ... -
Gnrh receptor gnrhr2bbα is expressed exclusively in lhb-expressing cells in Atlantic salmon male parr
Ciani, Elia; Fontaine, Romain; Maugars, Gersende Marie Aimee; Rasoul, Nourizadeh-Lillabadi; Andersson, Eva; Bogerd, Jan; von Krogh, Kristine; Weltzien, Finn-Arne (Peer reviewed; Journal article, 2020)Gonadotropin-releasing hormone (Gnrh) plays a major role in the regulation of physiological and behavioural processes related to reproduction. In the pituitary, it stimulates gonadotropin synthesis and release via activation ... -
Gonadotrope plasticity at cellular, population and structural levels: A comparison between fishes and mammals
Fontaine, Romain David; Ciani, Elia; Haug, Trude M; Hodne, Kjetil; Ager-Wick, Eirill; Baker, Dianne; Weltzien, Finn-Arne (Journal article; Peer reviewed, 2019)Often referred to as “the master gland”, the pituitary is a key organ controlling growth, maturation, and homeostasis in vertebrates. The anterior pituitary, which contains several hormone-producing cell types, is highly ... -
Healthy Brain-pituitary Slices for Electrophysiological Investigations of Pituitary Cells in Teleost Fish
Fontaine, Romain; Hodne, Kjetil; Weltzien, Finn-Arne (Journal article; Peer reviewed, 2018)Electrophysiological investigations of pituitary cells have been conducted in numerous vertebrate species, but very few in teleost fish. Among these, the clear majority have been performed on dissociated primary cells. To ... -
In Vitro Effects of Bisphenol A and Tetrabromobisphenol A on Cell Viability and Reproduction-Related Gene Expression in Pituitaries from Sexually Maturing Atlantic Cod (Gadus morhua L.)
von Krogh, Kristine; Weltzien, Finn-Arne; Haug, Trude; Nourizadeh-Lillabadi, Rasoul; Ropstad, Erik (Peer reviewed; Journal article, 2019) -
Long extensions with varicosity-like structures in gonadotrope Lh cells facilitate clustering in medaka pituitary culture
Grønlien, Heidi Kristine; Fontaine, Romain; Hodne, Kjetil; Tysseng, Linn Isabelle; Ager-Wick, Eirill; Weltzien, Finn-Arne; Haug, Trude M (Peer reviewed; Journal article, 2021) -
Medaka (Oryzias latipes) gonadotropins : production and developmental profiles, pharmacological characterization of their receptors, and establishment of a novel transgenic line tg(fshb:DsRed2)
Burow, Susann (PhD Thesis;2019:6, Doctoral thesis, 2019)The gonadotropins, follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh), produced in gonadotrope cells of the pituitary, possess key roles in the endocrine control of vertebrate puberty and reproduction as part ... -
Melatonin receptors in Atlantic salmon stimulate cAMP levels in heterologous cell lines and show season‐dependent daily variations in pituitary expression levels
Ciani, Elia; Fontaine, Romain; Maugars, Gersende Marie Aimee; Naama, Mizrahi; Mayer, Ian; Levavi-Sivan, Berta; Weltzien, Finn-Arne (Peer reviewed; Journal article, 2019)