Browsing Brage NMBU by Author "Tollefsen, Knut Erik"
Now showing items 1-20 of 31
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17α-Ethinylestradiol (EE2) effect on global gene expression in primary rainbow trout (Oncorhynchus mykiss) hepatocytes
Hultman, Maria Therese; Song, You; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2015) -
Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Tollefsen, Knut Erik; Alonzo, Frederic; Beresford, Nicholas A.; Brede, Dag Anders; Dufourcq-Sekatcheff, Elizabeth; Gilbin, Rodolphe; Horemans, Nele; Hurem, Selma; Laloi, Patrick; Maremonti, Erica; Oughton, Deborah Helen; Simon, Olivier; Song, You; Wood, Michael; Xie, Li; Frelon, Sandrine (Peer reviewed; Journal article, 2022) -
AOP Report: Inhibition of Chitin Synthase 1 Leading to Increased Mortality in Arthropods
Schmid, Simon; Song, You; Tollefsen, Knut Erik (Peer reviewed; Journal article, 2021) -
Assessment of a novel device for onsite integrative large-volume solid phase extraction of water samples to enable a comprehensive chemical and effect-based analysis
Schulze, Tobias; Ahel, Marijan; Ahlheim, Jorg; Ait-Aissa, Selim; Brion, Francois; Di Paolo, Carolina; Froment, Jean Francois; Hidasi, Anita O; Hollender, Juliane; Hollert, Henner; Hu, Meng; Kloss, Anett; Koprivica, Sanja; Krauss, Martin; Muz, Melis; Oswald, Peter; Petre, Margit; Schollee, Jennifer E; Seiler, Thomas-Benjamin; Shao, Ying; Slobodnik, Jaroslav; Sonavane, Manoj; Suter, Marc J-F; Tollefsen, Knut Erik; Tousova, Zuzana; Walz, Karl-Heinz; Brack, Werner (Journal article; Peer reviewed, 2017) -
Characterization of pesticide hazard and risk to freshwater algae under ecologically relevant exposure conditions in Norway
Haug, Linn Anette (Master thesis, 2017)Balansen i det akvatiske økosystemet er under konstant press fra menneskelig påvirkning, og store mengder forurensende stoffer slippes ut i vannforekomster i hele verden. Blant disse er pesticider en stor kilde til utslipp, ... -
Characterizing combined effects of antiestrogenic chemicals on vitellogenin production in rainbow trout (Oncorhynchus mykiss) hepatocytes
Hultman, Maria Thérése; Petersen, Karina; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017) -
Deciphering the Combined Effects of Environmental Stressors on Gene Transcription: A Conceptual Approach
Song, You; Asselman, Jana; De Schamphelaere, Karel A. C.; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)The use of classical mixture toxicity models to predict the combined effects of environmental stressors based on toxicogenomics (OMICS) data is still in its infancy. Although several studies have made attempts to implement ... -
Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development
Song, You; Villeneuve, Daniel L.; Toyota, Kenji; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017) -
Effect of nanoplastics in the marine organism Tisbe battagliai
Lilje, Kristin (Master thesis, 2019)Plastic is a material made out of polymer chains derived from oil and gas, and together with additives these polymers have numerous applications. Plastic is used in daily life as wrapping around food, in cosmetics and in ... -
Evaluation of primary rainbow trout (Oncorhynchus mykiss ) hepatocytes suitability as a screening assay for estrogen receptor agonists
Hultman, Maria Therese (PhD Thesis;2016:47, Doctoral thesis, 2017-07-12)Regulatory legislations on chemicals have in recent years become more stringent, requiring more toxicological evaluation. The increased toxicological testing have resulted in a stronger effort to implement the 3Rs (Refinement, ... -
Evaluation of the aquatic bryophyte Fontinalis antipyretica for laboratory and field toxicity studies
Dahl, Lina Agneberg (Master thesis, 2021)Fontinalis antipyretica is an ecologically important aquatic moss in boreal streams. Bioassays using this species provide information of effects at the base of the food chain. The present study assessed toxicological effects ... -
Gamma radiation induces dose-dependent oxidative stress and transcriptional alterations in the freshwater crustacean Daphnia magna
Gomes, Tania; Song, You; Brede, Dag Anders; Xie, Li; Gutzkow, Kristine Bjerve; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018) -
Hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to gamma radiation and depleted uranium singly and in combination
Song, You; Salbu, Brit; Teien, Hans-Christian; Evensen, Øystein; Lind, Ole Christian; Rosseland, Bjørn Olav; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2016) -
Impact of speciation and uptake on toxicity of single metals and metal mixtures to the marine copepod Tisbe battagliai
Jarosz, Emil (PhD thesis;2023:37, Doctoral thesis, 2023)In coastal waters a wide variety of metals are present in different physicochemical forms (low molecular mass species, colloids, aggregates, or particulate metal), usually as mixtures of different metals. High risk of ... -
Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development
Toyota, Kenji; Watanabe, Haruna; Hirano, Masashi; Abe, Ryoko; Miyakawa, Hitoshi; Song, You; Sato, Tomomi; Miyagawa, Shinichi; Tollefsen, Knut Erik; Yamamoto, Hiroshi; Tatarazako, Norihisa; Iguchi, Taisen (Peer reviewed; Journal article, 2021)Juvenile hormone (JH) are a family of multifunctional hormones regulating larval development, molting, metamorphosis, reproduction, and phenotypic plasticity in arthropods. Based on its importance in arthropod life histories, ... -
Linking mode of action of the model respiratory and photosynthesis uncoupler 3,5-dichlorophenol to adverse outcomes in Lemna minor
Xie, Li; Gomes, Tania; Solhaug, Knut Asbjørn; Song, You; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)Standard chemical toxicity testing guidelines using aquatic plant Lemna minor have been developed by several international standardisation organisations. Although being highly useful for regulatory purposes by focusing on ... -
Metal mixtures, assessing speciation models to predict uptake in Brown Trout (Salmo trutta)
Napast, Denis (Master thesis, 2018)Alum shale is an organic-rich rock which contains high concentrations of U, Ni, V, Mo, Co, Cu, Zn, As and other metals. These metals are released into the environment by human actives and rock weathering. Many different ... -
Mortality and transcriptional effects of inorganic mercury in the marine copepod Calanus finmarchicus
Tollefsen, Knut Erik; Song, You; Høgåsen, Tore; Øverjordet, Ida Beathe; Altin, Dag; Hansen, Bjørn Henrik (Peer reviewed; Journal article, 2017)Inorganic mercury (Hg) is highly toxic to organisms including crustaceans and displays multiple toxic modes of action (MoA). The main aim of this investigation was to assess the acute and sublethal toxicity mediated by ... -
No evidence of a protective or cumulative negative effect of UV-B on growth inhibition induced by gamma radiation in Scots pine (Pinus sylvestris) seedlings
Blagojevic, Dajana; Lee, YeonKyeong; Xie, Li; Brede, Dag A; Nybakken, Line; Lind, Ole Christian; Tollefsen, Knut Erik; Salbu, Brit; Solhaug, Knut Asbjørn; Olsen, Jorunn E (Peer reviewed; Journal article, 2019) -
Primary hepatocytes from Arctic char (Salvelinus alpinus) as a relevant Arctic in vitro model for screening contaminants and environmental extracts
Petersen, Karina; Hultman, Maria T; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017)