Browsing Brage NMBU by Author "Song, You"
Now showing items 1-20 of 33
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17α-Ethinylestradiol (EE2) effect on global gene expression in primary rainbow trout (Oncorhynchus mykiss) hepatocytes
Hultman, Maria Therese; Song, You; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2015) -
Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Tollefsen, Knut Erik; Alonzo, Frederic; Beresford, Nicholas A.; Brede, Dag Anders; Dufourcq-Sekatcheff, Elizabeth; Gilbin, Rodolphe; Horemans, Nele; Hurem, Selma; Laloi, Patrick; Maremonti, Erica; Oughton, Deborah Helen; Simon, Olivier; Song, You; Wood, Michael; Xie, Li; Frelon, Sandrine (Peer reviewed; Journal article, 2022) -
Age and Synchronization of Daphnia magna Affect Sensitivity to Teflubenzuron in Acute Standardized Toxicity Tests
Nordblad Schmidt, Simon; Rundberget, Thomas; Song, You; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2023) -
AOP Report: Inhibition of Chitin Synthase 1 Leading to Increased Mortality in Arthropods
Schmid, Simon; Song, You; Tollefsen, Knut Erik (Peer reviewed; Journal article, 2021) -
Comparison of piecewise structural equation modeling and Bayesian network for de novo construction of a quantitative adverse outcome pathway network
Cao, Yang; Moe, S. Jannicke; De Bin, Riccardo; Tollefsen, Knut-Erik; Song, You (Journal article; Peer reviewed, 2023)Quantitative adverse outcome pathway network (qAOPN) is gaining momentum due to the predictive nature, alignment with quantitative risk assessment and great potential as a computational new approach methodology (NAM) to ... -
Comparison of structural equation modeling and Bayesian network for de novo construction of a quantitative adverse outcome pathway network
Cao, Yang; Moe, S. Jannicke; De Bin, Riccardo; Tollefsen, Knut-Erik; Song, You (Peer reviewed; Journal article, 2022)Quantitative adverse outcome pathway network (qAOPN) is gaining momentum due to the predictive nature, alignment with quantitative risk assessment and great potential as a computational new approach methodology (NAM) to ... -
Deciphering the Combined Effects of Environmental Stressors on Gene Transcription: A Conceptual Approach
Song, You; Asselman, Jana; De Schamphelaere, Karel A. C.; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)The use of classical mixture toxicity models to predict the combined effects of environmental stressors based on toxicogenomics (OMICS) data is still in its infancy. Although several studies have made attempts to implement ... -
Dose-dependent hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to sublethal doses of gamma radiation
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014) -
Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development
Song, You; Villeneuve, Daniel L.; Toyota, Kenji; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017) -
Effects of artificial ultraviolet B radiation on the macrophyte Lemna minor: a conceptual study for toxicity pathway characterization
Xie, Li; Solhaug, Knut Asbjørn; Song, You; Johnsen, Bjørn; Olsen, Jorunn Elisabeth; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Macrophytes inhabit waterways around the world and are used in hydroponics or aquaponics for different purposes such as feed and wastewater treatment and are thus exposed to elevated levels of UVB from natural and artificial ... -
Environmental risk assessment of combined effects in aquatic ecotoxicology: A discussion paper
Beyer, Jonny; Petersen, Karina; Song, You; Ruus, Anders; Grung, Merete; Bakke, Torgeir Heggelund; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014) -
Epigenetic, transcriptional and phenotypic responses in Daphnia magna exposed to low-level ionizing radiation
Thaulow, Jens; Song, You; Lindeman, Leif C; Kamstra, Jorke H; YeonKyeong, Lee; Xie, Li; Aleström, Peter; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Ionizing radiation is known to induce oxidative stress and DNA damage as well as epigenetic effects in aquatic organisms. Epigenetic changes can be part of the adaptive responses to protect organisms from radiation-induced ... -
Epigenetic, transcriptional and phenotypic responses in two generations of Daphnia magna exposed to the DNA methylation inhibitor 5-Azacytidine
Lindeman, Leif Christopher; Thaulow, Jens; Song, You; Kamstra, Jorke H; Xie, Li; Asselman, Jana; Alestrøm, Peter; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2019)The water flea Daphnia magna is a keystone species in freshwater ecosystems and has been widely used as a model organism in environmental ecotoxicology. This aquatic crustacean is sensitive to environmental stressors and ... -
Gamma radiation induces dose-dependent oxidative stress and transcriptional alterations in the freshwater crustacean Daphnia magna
Gomes, Tania; Song, You; Brede, Dag Anders; Xie, Li; Gutzkow, Kristine Bjerve; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018) -
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Høgåsen, Tore; Tollefsen, Knut-Erik (Journal article, 2014)Potential environmental hazards of radionuclides are often studied at the individual level. Sufficient toxicogenomics data at the molecular/cellular level for understanding the effects and modes of toxic action (MoAs) of ... -
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Høgåsen, Tore; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014)Potential environmental hazards of radionuclides are often studied at the individual level. Sufficient toxicogenomics data at the molecular/cellular level for understanding the effects and modes of toxic action (MoAs) of ... -
Hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to gamma radiation and depleted uranium singly and in combination
Song, You; Salbu, Brit; Teien, Hans-Christian; Evensen, Øystein; Lind, Ole Christian; Rosseland, Bjørn Olav; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2016) -
Hepatic transcriptomic profiling reveals early toxicological mechanisms of uranium in Atlantic salmon (Salmo salar)
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Høgåsen, Tore; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014) -
Integrative assessment of low-dose gamma radiation effects on Daphnia magna reproduction: Toxicity pathway assembly and AOP development
Song, You; Xie, Li; Lee, YeonKyeong; Brede, Dag Anders; Lyne, Fern; Kassaye, Yetneberk Ayalew; Thaulow, Jens; Caldwell, Gary S.; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020) -
Juvenile hormone synthesis and signaling disruption triggering male offspring induction and population decline in cladocerans (water flea): Review and adverse outcome pathway development
Toyota, Kenji; Watanabe, Haruna; Hirano, Masashi; Abe, Ryoko; Miyakawa, Hitoshi; Song, You; Sato, Tomomi; Miyagawa, Shinichi; Tollefsen, Knut Erik; Yamamoto, Hiroshi; Tatarazako, Norihisa; Iguchi, Taisen (Peer reviewed; Journal article, 2021)Juvenile hormone (JH) are a family of multifunctional hormones regulating larval development, molting, metamorphosis, reproduction, and phenotypic plasticity in arthropods. Based on its importance in arthropod life histories, ...