Browsing Brage NMBU by Author "Song, You"
Now showing items 1-20 of 24
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17α-Ethinylestradiol (EE2) effect on global gene expression in primary rainbow trout (Oncorhynchus mykiss) hepatocytes
Hultman, Maria Therese; Song, You; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2015) -
AOP Report: Inhibition of Chitin Synthase 1 Leading to Increased Mortality in Arthropods
Schmid, Simon; Song, You; Tollefsen, Knut Erik (Peer reviewed; Journal article, 2021) -
Deciphering the Combined Effects of Environmental Stressors on Gene Transcription: A Conceptual Approach
Song, You; Asselman, Jana; De Schamphelaere, Karel A. C.; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)The use of classical mixture toxicity models to predict the combined effects of environmental stressors based on toxicogenomics (OMICS) data is still in its infancy. Although several studies have made attempts to implement ... -
Dose-dependent hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to sublethal doses of gamma radiation
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014) -
Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development
Song, You; Villeneuve, Daniel L.; Toyota, Kenji; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017) -
Effects of artificial ultraviolet B radiation on the macrophyte Lemna minor: a conceptual study for toxicity pathway characterization
Xie, Li; Solhaug, Knut Asbjørn; Song, You; Johnsen, Bjørn; Olsen, Jorunn Elisabeth; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Macrophytes inhabit waterways around the world and are used in hydroponics or aquaponics for different purposes such as feed and wastewater treatment and are thus exposed to elevated levels of UVB from natural and artificial ... -
Environmental risk assessment of combined effects in aquatic ecotoxicology: A discussion paper
Beyer, Jonny; Petersen, Karina; Song, You; Ruus, Anders; Grung, Merete; Bakke, Torgeir Heggelund; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014) -
Epigenetic, transcriptional and phenotypic responses in Daphnia magna exposed to low-level ionizing radiation
Thaulow, Jens; Song, You; Lindeman, Leif C; Kamstra, Jorke H; YeonKyeong, Lee; Xie, Li; Aleström, Peter; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Ionizing radiation is known to induce oxidative stress and DNA damage as well as epigenetic effects in aquatic organisms. Epigenetic changes can be part of the adaptive responses to protect organisms from radiation-induced ... -
Epigenetic, transcriptional and phenotypic responses in two generations of Daphnia magna exposed to the DNA methylation inhibitor 5-Azacytidine
Lindeman, Leif Christopher; Thaulow, Jens; Song, You; Kamstra, Jorke H; Xie, Li; Asselman, Jana; Alestrøm, Peter; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2019)The water flea Daphnia magna is a keystone species in freshwater ecosystems and has been widely used as a model organism in environmental ecotoxicology. This aquatic crustacean is sensitive to environmental stressors and ... -
Gamma radiation induces dose-dependent oxidative stress and transcriptional alterations in the freshwater crustacean Daphnia magna
Gomes, Tania; Song, You; Brede, Dag Anders; Xie, Li; Gutzkow, Kristine Bjerve; Salbu, Brit; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018) -
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Høgåsen, Tore; Tollefsen, Knut-Erik (Journal article, 2014)Potential environmental hazards of radionuclides are often studied at the individual level. Sufficient toxicogenomics data at the molecular/cellular level for understanding the effects and modes of toxic action (MoAs) of ... -
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Høgåsen, Tore; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014)Potential environmental hazards of radionuclides are often studied at the individual level. Sufficient toxicogenomics data at the molecular/cellular level for understanding the effects and modes of toxic action (MoAs) of ... -
Hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to gamma radiation and depleted uranium singly and in combination
Song, You; Salbu, Brit; Teien, Hans-Christian; Evensen, Øystein; Lind, Ole Christian; Rosseland, Bjørn Olav; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2016) -
Hepatic transcriptomic profiling reveals early toxicological mechanisms of uranium in Atlantic salmon (Salmo salar)
Song, You; Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie; Rosseland, Bjørn Olav; Høgåsen, Tore; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2014) -
Integrative assessment of low-dose gamma radiation effects on Daphnia magna reproduction: Toxicity pathway assembly and AOP development
Song, You; Xie, Li; Lee, YeonKyeong; Brede, Dag Anders; Lyne, Fern; Kassaye, Yetneberk Ayalew; Thaulow, Jens; Caldwell, Gary S.; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020) -
Linking mode of action of the model respiratory and photosynthesis uncoupler 3,5-dichlorophenol to adverse outcomes in Lemna minor
Xie, Li; Gomes, Tania; Solhaug, Knut Asbjørn; Song, You; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2018)Standard chemical toxicity testing guidelines using aquatic plant Lemna minor have been developed by several international standardisation organisations. Although being highly useful for regulatory purposes by focusing on ... -
Modes of action and adverse effects of gamma radiation in an aquatic macrophyte Lemna minor
Xie, Li; Solhaug, Knut Asbjørn; Song, You; Brede, Dag Anders; Lind, Ole Christian; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2019)High dose rates of ionizing radiation have been reported to cause adverse effects such as reduction in reproduction and growth, and damage to protein and lipids in primary producers. However, the relevant effects of ionizing ... -
Mortality and transcriptional effects of inorganic mercury in the marine copepod Calanus finmarchicus
Tollefsen, Knut Erik; Song, You; Høgåsen, Tore; Øverjordet, Ida Beathe; Altin, Dag; Hansen, Bjørn Henrik (Peer reviewed; Journal article, 2017)Inorganic mercury (Hg) is highly toxic to organisms including crustaceans and displays multiple toxic modes of action (MoA). The main aim of this investigation was to assess the acute and sublethal toxicity mediated by ... -
De novo Development of a Quantitative Adverse Outcome Pathway (qAOP) Network for Ultraviolet B (UVB) Radiation Using Targeted Laboratory Tests and Automated Data Mining
Song, You; Xie, Li; Lee, YeonKyeong; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Ultraviolet B (UVB) radiation is a natural non-chemical stressor posing potential hazards to organisms such as planktonic crustaceans. The present study was conducted to revisit the lethal effects of UVB on crustaceans, ... -
Release of chitobiase as an indicator of potential molting disruption in juvenile Daphnia magna exposed to the ecdysone receptor agonist 20-hydroxyecdysone
Song, You; Evenseth, Linn Mari; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Peer reviewed, 2017)