Blar i Brage NMBU på forfatter "Sandvik, Guro Katrine"
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Development of a method to compare sgRNA expression driven by heterologous and endogenous U6 promoters in an Atlantic salmon head kidney cell line
Regmi, Axmee (Master thesis, 2021)Infectious diseases have negative impacts on fish welfare and sustainable aquaculture. Knowledge on host pathogen relationship and genes responsible for disease resistance could lead to development of vaccines and therapeutics ... -
Development of lentiviral technology for use in Atlantic salmon
Andreassen, Sara Stenmark (Master thesis, 2022)Lentiviral vectors are used to deliver and stably integrate genetic material into the genome of cells. When combined with CRISPR based gene editing technology, targeted editing of one or many host genes in a pooled format ... -
Prime editing in zebrafish and Atlantic salmon : exploring a new CRISPR technique in non-mammalian species
Bryhni, Jenny Heyerdahl (Master thesis, 2022)The CRISPR-Cas system has enabled precise genome editing in a multitude of organisms, and gene knockout experiments can now be done with relative ease due to the simplicity of the system. However, unintended genomic ... -
Pseudotyping lentiviral vectors for transduction of Salmo salar cells using glycoprotein from infectious salmon anaemia virus
Låstad, Thea Marie (Master thesis, 2023)Lentivirus is commonly used as vector for CRISPR applications. The common vector system utilises glycoproteins from the vesicular stomatitis virus (VSV-G). This vector has broad a tropism, including the salmonid species ... -
RFamide peptides in early vertebrate development
Sandvik, Guro Katrine; Hodne, Kjetil; Haug, Trude M; Okubo, Kataaki; Weltzien, Finn-Arne (Journal article; Peer reviewed, 2014) -
Tracking GnRH neurons in vivo following CRISPR knock out of Six6 in Atlantic salmon
Nesset, Thomas (Master thesis, 2021)Gonadotropin releasing hormone (GnRH) is a conserved neuroendocrine decapeptide, crucial for the onset of puberty and for the functioning of the hypothalamic-pituitary-gonadal axis (HPG). The homeodomain protein sine oculis ...