• Activation of innate immune genes in caprine blood leukocytes after systemic endotoxin challenge 

      Heegaard, Peter M.H.; Tranulis, Michael A.; Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Ersdal, Cecilie; Skovgaard, Kerstin (Journal article; Peer reviewed, 2016)
    • Demyelinating polyneuropathy in goats lacking prion protein. 

      Skedsmo, Fredrik Strebel; Malachin, Giulia; Våge, Dag Inge; Hammervold, Mie Marie; Salvesen, Øyvind; Ersdal, Cecilie; Ranheim, Birgit; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Bruheim, Per; Jäderlund, Karin Hultin; Matiasek, Kaspar; Espenes, Arild; Tranulis, Michael A. (Peer reviewed; Journal article, 2019)
      Studies in mice with ablation of Prnp, the gene that encodes the cellular prion protein (PrPC), have led to the hypothesis that PrPC is important for peripheral nerve myelin maintenance. Here, we have used a nontransgenic ...
    • Feasibility of telerehabilitation for heart failure patients inaccessible for outpatient rehabilitation 

      Lundgren, Kari Margrethe; Langlo, Knut Asbjørn Rise; Salvesen, Øyvind; Zanaboni, Paolo; Cittanti, Elisa; Mo, Rune; Ellingsen, Øyvind; Dalen, Håvard; Aksetøy, Inger-Lise Aamot (Peer reviewed; Journal article, 2023)
    • Goats naturally devoid of PrPC are resistant to scrapie 

      Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020)
      Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the “protein-only” hypothesis, the normal host-encoded prion protein (PrPC) is converted into a pathological ...
    • Goats naturally devoid of PrPC are resistant to scrapie 

      Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020)
      Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the "protein-only" hypothesis, the normal host-encoded prion protein (PrPC) is converted into a pathological ...
    • LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface 

      Salvesen, Øyvind; Reiten, Malin Rokseth (Journal article; Peer reviewed, 2017)
    • No evidence of uptake or propagation of reindeer CWD prions in environmentally exposed sheep 

      Harpaz, Erez; Salvesen, Øyvind; Rauset, Geir Rune; Aqsa, Mahmood; Tran, Linh Dinh Thoai; Ytrehus, Bjørnar; Benestad, Sylvie L.; Tranulis, Michael A.; Espenes, Arild; Ersdal, Cecilie (Peer reviewed; Journal article, 2022)
      Background Chronic wasting disease (CWD) is a prion disease of cervids first reported in North America in the 1960s. In Europe, CWD was first diagnosed in 2016 in a wild reindeer in Norway. Detection of two more cases in ...
    • The cellular prion protein and the inflammatory response 

      Salvesen, Øyvind (PhD Thesis;2017:81, Doctoral thesis, 2017)
      The cellular prion protein (PrPC) is known for its pivotal role in the development of prion diseases, such as Creutzfeldt-Jakob disease in humans and scrapie in small ruminants. In these diseases, PrPC is converted into a ...
    • The prion protein in neuroimmune crosstalk 

      Salvesen, Øyvind; Tazelt, Jörg; Tranulis, Michael A. (Journal article; Peer reviewed, 2018)
      The cellular prion protein (PrPC) is a medium-sized glycoprotein, attached to the cell surface by a glycosylphosphatidylinositol anchor. PrPC is encoded by a single-copy gene, PRNP, which is abundantly expressed in the ...