Blar i Brage NMBU på forfatter "Ovchinnikov, Kirill"
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A bacteriocin-based antimicrobial formulation to effectively disrupt the cell viability of methicillin-resistant Staphylococcus aureus (MRSA) biofilms
Kranjec, Christian; Ovchinnikov, Kirill; Grønseth, Torstein; Ebineshan, Kumar; Srikantam, Aparna; Diep, Dzung B. (Peer reviewed; Journal article, 2020)1463 Accesses 1 Citations 21 Altmetric Metricsdetails Abstract Antibiotic-resistant and biofilm-associated infections brought about by methicillin-resistant Staphylococcus aureus (MRSA) strains is a pressing ... -
Bacteriocins Revitalize Non-Effective Penicillin G to Overcome Methicillin-Resistant Staphylococcus pseudintermedius
Ovchinnikov, Kirill; Kranjec, Christian; Thorstensen, Tage; Carlsen, Harald; Diep, Dzung B. (Peer reviewed; Journal article, 2022)The rise of antibiotic-resistant bacteria is among the biggest challenges in human and veterinary medicine. One of the major factors that contributes to resistance is use of frontline clinical antibiotics in veterinary ... -
Lugol's solution and Gentian violet eradicate methicillin-resistant Staphylococcus aureus biofilm in skin wound infections
Grønseth, Torstein; Ovchinnikov, Kirill; Carlsen, Harald; Saltyte Benth, Jurate; Diep, Dzung B.; Von Unge, Magnus; Silvola, Juha Tapio (Peer reviewed; Journal article, 2022)The study aimed to evaluate the antibacterial efficacy of Lugol's solution 5% and Gentian violet 1% against methicillin-resistant Staphylococcus aureus (MRSA) biofilm in vivo. The bactericidal efficacy for treatment of ... -
Over 2000-Fold Increased Production of the Leaderless Bacteriocin Garvicin KS by Increasing Gene Dose and Optimization of Culture Conditions
Telke, Amar; Ovchinnikov, Kirill; Vuoristo, Kiira; Mathiesen, Geir; Thorstensen, Tage; Diep, Dzung B. (Journal article; Peer reviewed, 2019)The leaderless bacteriocin Garvicin KS (GarKS) is a potent antimicrobial, being active against a wide range of important pathogens. GarKS production by the native producer Lactococcus garvieae KS1546 is, however, relatively ... -
Purification and characterisation of new bacteriocins
Hestad, Kai Arne (Master thesis, 2020)Not long after the discovery of the first antibiotics in the 20th century, bacteria resistant to this treatment has appeared and the spread of their genes can occur in several ways. This development has just increased, and ... -
Recombinant production of the lantibiotic nisin using Corynebacterium glutamicum in a two-step process
Weixler, D.; Berghoff, M; Ovchinnikov, Kirill; Reich, Sebastian; Goldbeck, Oliver; Seibold, Gerd M.; Wittmann, Christoph; Bar, Nadav S; Eikmanns, Bernhard J; Diep, Dzung B.; Riedel, Christian U. (Peer reviewed; Journal article, 2022) -
Successful development of bacteriocins into therapeutic formulation for treatment of MRSA skin infection in a murine model
Ovchinnikov, Kirill; Kranjec, Christian; Thorstensen, Tage; Carlsen, Harald; Diep, Dzung B. (Peer reviewed; Journal article, 2020)The emergence of antibiotic-resistant pathogens has caused a serious worldwide problem in infection treatment in recent years. One of the pathogens is methicillin-resistant Staphylococcus aureus (MRSA), which is a major ... -
Synthesis of Thioridazine
Antonsen, Simen Gjelseth; Monsen, Erling Berge; Ovchinnikov, Kirill; Nolsøe, Jens Mortansson Jelstrup; Ekeberg, Dag; Kristiansen, Jette E.; Diep, Dzung B.; Stenstrøm, Yngve H. (Journal article; Peer reviewed, 2020) -
Synthesis of Thioridazine
Antonsen, Simen Gjelseth; Monsen, Erling Berge; Ovchinnikov, Kirill; Nolsøe, Jens Mortansson Jelstrup; Ekeberg, Dag; Kristiansen, Jette E.; Diep, Dzung B.; Stenstrøm, Yngve H. (Peer reviewed; Journal article, 2020)Thioridazine, a well-known antipsychotic drug, has shown promising effects on several bacterial strains (including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus). Suppressive effects towards ... -
The leaderless bacteriocin enterocin K1 is highly potent against Enterococcus faecium: A study on structure, target spectrum and receptor
Ovchinnikov, Kirill; Kristiansen, Per Eugen; Straume, Daniel; Jensen, Marianne Slang; Aleksandrzak-Piekarczyk, Tamara; Nes, Ingolf; Diep, Dzung Bao (Journal article; Peer reviewed, 2017) -
The novel bacteriocin romsacin from Staphylococcus haemolyticus inhibits Gram-positive WHO priority pathogens
Wolden, Runa; Ovchinnikov, Kirill; Venter, Hermoine Jean; Oftedal, Thomas; Diep, Bao Dung; Cavanagh, Jorunn Pauline (Peer reviewed; Journal article, 2023)