• Effects of pH on steam explosion extraction of acetylated galactoglucomannan from Norway spruce 

      Michalak, Leszek; Knutsen, Svein Halvor; Aarum, Ida Synnøve; Westereng, Bjørge (Journal article; Peer reviewed, 2018)
      Background: Acetylated galactoglucomannan (AcGGM) is a complex hemicellulose found in softwoods such as Norway spruce (Picea abies). AcGGM has a large potential as a biorefinery feedstock and source of oligosaccharides for ...
    • Exploring acetylated galactoglucomannan as a source of prebiotics 

      Michalak, Leszek (Doctoral thesis, 2018)
      The wood and paper industry in Norway and worldwide suffers from low demand and low prices. Developing consolidated biorefinery solutions to generate higher value products from woody biomass could be a viable alternative ...
    • Human Gut Faecalibacterium prausnitzii Deploys a Highly Efficient Conserved System To Cross-Feed on β-Mannan-Derived Oligosaccharides 

      Lindstad, Lars Jordhøy; Lo, G; Leivers, Shaun Allan; Lu, Z; Michalak, Leszek; Pereira, GV; Kjendseth, Åsmund Røhr; Martens, Eric C.; McKee, LS; Louis, Petra; Duncan, S; Westereng, Bjørge; Pope, Phillip; Leanti La Rosa, Sabina (Peer reviewed; Journal article, 2021)
    • The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans 

      Leanti La Rosa, Sabina; Leth, Maria Louise; Michalak, Leszek; Hansen, Morten Ejby; Pudlo, Nicholas; Glowacki, Robert; Pereira, Gabriel; Workman, Christopher; Arntzen, Magnus Øverlie; Pope, Phillip; Martens, Eric C.; Hachem, Maher Abou; Westereng, Bjørge (Peer reviewed; Journal article, 2019)
      β-Mannans are plant cell wall polysaccharides that are commonly found in human diets. However, a mechanistic understanding into the key populations that degrade this glycan is absent, especially for the dominant Firmicutes ...
    • Microbiota-directed fibre activates both targeted and secondary metabolic shifts in the distal gut 

      Michalak, Leszek; Gaby, John Christian; Lagos, Leidy; Leanti La Rosa, Sabina; Hvidsten, Torgeir Rhoden; Tetard-Jones, Catherine; Willats, William G.T.; Terrapon, Nicolas; Lombard, Vincent; Henrissat, Bernard; Dröge, Johannes; Arntzen, Magnus Øverlie; Hagen, Live Heldal; Øverland, Margareth; Pope, Phillip Byron; Westereng, Bjørge (Peer reviewed; Journal article, 2020)
      Beneficial modulation of the gut microbiome has high-impact implications not only in humans, but also in livestock that sustain our current societal needs. In this context, we have tailored an acetylated galactoglucomannan ...