Blar i Brage NMBU på forfatter "Mathiesen, Geir"

Ankring av Chlamydia trachomatis antigener på overflaten av Lactobacillus plantarum

Myrbråten, Ine (Master thesis, 2016-11-17)

Dette studiet er en del av et større prosjekt der det langsiktige målet er å utvikle slimhinnevaksiner med melkesyrebakterier som leveringsvektorer. Melkesyrebakterier ansees som gode kandidater til dette formål, da de ...

Celleveggankring av Mycobacterium tuberculosis-antigener på overflaten til Lactobacillus plantarum

Berggreen, Hanne (Master thesis, 2020)

Denne oppgaven er en del av et større forskningsprosjekt hvor det langsiktige målet er å utvikle en slimhinnevaksine mot tuberkulose, hvor melkesyrebakterier benyttes som leveringsvektor av antigener. Melkesyrebakterier ...

Comparison of eight Lactobacillus species for delivery of surface-displayed mycobacterial antigen

Kuczkowska, Katarzyna; Øverland, Lise; Cardoso Da Rocha, Sergio Domingos; Eijsink, Vincent; Mathiesen, Geir (Journal article; Peer reviewed, 2019)

Lactobacillus spp. comprise a large group of Gram-positive lactic acid bacteria with varying physiological, ecological and immunomodulatory properties that are widely exploited by mankind, primarily in food production and ...

Computational and Experimental Analysis of the Secretome of Methylococcus capsulatus (Bath)

Indrelid, Stine; Mathiesen, Geir; Jacobsen, Morten; Lea, Tor Erling; Kleiveland, Charlotte Ramstad (Journal article; Peer reviewed, 2014)

Constitutive expression and anchoring of Mycobacterium tuberculosis antigens in Lactobacillus plantarum

Wiig, Solveig Birkedal (Master thesis, 2020)

Tuberculosis is the leading cause of death caused by a single agent worldwide. A new and effective vaccine against this infection is therefore imperative. This study is a part of a larger project where the long-term goal ...

CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in Lactobacillus plantarum.

Myrbråten, Ine Storaker; Wiull, Kamilla; Salehian, Zhian; Håvarstein, Leiv Sigve; Straume, Daniel; Mathiesen, Geir; Kjos, Morten (Journal article; Peer reviewed, 2019)

Display of a β-mannanase and a chitosanase on the cell surface of Lactobacillus plantarum towards the development of whole-cell biocatalysts

Nguyen, H-M; Mathiesen, Geir; Stelzer, Elena Maria; Pham, Mai Lan; Kuczkowska, Katarzyna; Mackenzie, Alasdair; Wittrup_Agger, Jane; Eijsink, Vincentius Gerardus Henricus; Yamabhai, Montarop; Peterbauer, Clemens; Haltrich, Dietmar; Nguyen, T-H (Journal article; Peer reviewed, 2016)

Display of recombinant proteins at the surface of Lactic Acid Bacteria: strategies and applications

Michon, C; Langella, P; Eijsink, Vincent; Mathiesen, Geir; Chatel, JM (Journal article; Peer reviewed, 2016)

Expression of endoglucanases in Pichia pastoris under control of the GAP promoter

Varnai, Aniko; Tang, Campbell; Bengtsson, Oskar; Atterton, Andrew; Mathiesen, Geir; Eijsink, Vincent (Journal article; Peer reviewed, 2014)

Heterologous expression of a recombinant lactobacillal β-galactosidase in Lactobacillus plantarum: effect of different parameters on the sakacin P-based expression system

Nguyen, TT; Nguyen, H-M; Mathiesen, Geir; Eijsink, Vincent; Peterbauer, CK; Haltrich, Dietmar; Nguyen, T-H (Journal article; Peer reviewed, 2015)

Heterologous protein secretion in lactobacilli with modified pSIP vectors

Maudal, Kristina; Axelsson, Lars; Rud, ida; Eijsink, Vincent; Mathiesen, Geir; Karlskås, Ingrid Lea (Journal article; Peer reviewed, 2014)

Identification of RseP as a receptor for hybrid bacteriocin H1 in emerging pathogen Staphylococcus haemolyticus

Bartkiewicz, Karolina Teresa (Master thesis, 2020)

Staphylococcus haemolyticus is an emerging pathogen which may transfer multi-drug resistance genes to highly virulent Staphylococcus species. S. haemolyticus is a biofilm-producing bacterium and one of the most frequent ...

Implementation of a two-plasmid CRISPR/Cas9 system in Lactobacillus plantarum : a new approach in the development of a novel vaccine against Mycobacterium tuberculosis

Wiull, Kamilla (Master thesis, 2018)

Tuberculosis (TB) is the leading cause of deaths from a single infectious agent, and in 2017 1.7 million people died from TB. To date the only available vaccine against the disease is the bacille Calmette-Guèrin (BCG) ...

Lactobacillus plantarum displaying CCL3 chemokine in fusion with HIV-1 Gag derived antigen causes increased recruitment of T cells

Kuczkowska, Katarzyna; Mathiesen, Geir; Eijsink, Vincent; Øynebråten, Inger (Journal article; Peer reviewed, 2015)

Lactobacillus plantarum producing a Chlamydia trachomatis antigen induces a specific IgA response after mucosal booster immunization

Kuczkowska, Katarzyna; Myrbråten, Ine; Øverland, Lise; Eijsink, Vincentius Gerardus Henricus; Follmann, F; Mathiesen, Geir; Dietrich, J (Journal article; Peer reviewed, 2017)

Over 2000-Fold Increased Production of the Leaderless Bacteriocin Garvicin KS by Increasing Gene Dose and Optimization of Culture Conditions

Telke, Amar; Ovchinnikov, Kirill; Vuoristo, Kiira; Mathiesen, Geir; Thorstensen, Tage; Diep, Dzung B. (Journal article; Peer reviewed, 2019)

The leaderless bacteriocin Garvicin KS (GarKS) is a potent antimicrobial, being active against a wide range of important pathogens. GarKS production by the native producer Lactococcus garvieae KS1546 is, however, relatively ...

Production of potential immune modulating proteins from Methylococcus capsulatus Bath and characterization of their putative roles in inflammation

Aaen, Kristin Hovden (Master thesis, 2019)

Commensal microbes have for a long time been considered important for the function and development of the human immune system. Later studies also highlight the beneficial potential of non-commensals to human health. The ...