Blar i Brage NMBU på forfatter "Mathiesen, Geir"
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Ankring av Chlamydia trachomatis antigener på overflaten av Lactobacillus plantarum
Myrbråten, Ine (Master thesis, 2016-11-17)Dette studiet er en del av et større prosjekt der det langsiktige målet er å utvikle slimhinnevaksiner med melkesyrebakterier som leveringsvektorer. Melkesyrebakterier ansees som gode kandidater til dette formål, da de ... -
Celleveggankring av Mycobacterium tuberculosis-antigener på overflaten til Lactobacillus plantarum
Berggreen, Hanne (Master thesis, 2020)Denne oppgaven er en del av et større forskningsprosjekt hvor det langsiktige målet er å utvikle en slimhinnevaksine mot tuberkulose, hvor melkesyrebakterier benyttes som leveringsvektor av antigener. Melkesyrebakterier ... -
Comparison of eight Lactobacillus species for delivery of surface-displayed mycobacterial antigen
Kuczkowska, Katarzyna; Øverland, Lise; Cardoso Da Rocha, Sergio Domingos; Eijsink, Vincent; Mathiesen, Geir (Journal article; Peer reviewed, 2019)Lactobacillus spp. comprise a large group of Gram-positive lactic acid bacteria with varying physiological, ecological and immunomodulatory properties that are widely exploited by mankind, primarily in food production and ... -
Computational and Experimental Analysis of the Secretome of Methylococcus capsulatus (Bath)
Indrelid, Stine; Mathiesen, Geir; Jacobsen, Morten; Lea, Tor Erling; Kleiveland, Charlotte Ramstad (Journal article; Peer reviewed, 2014) -
Constitutive expression and anchoring of Mycobacterium tuberculosis antigens in Lactobacillus plantarum
Wiig, Solveig Birkedal (Master thesis, 2020)Tuberculosis is the leading cause of death caused by a single agent worldwide. A new and effective vaccine against this infection is therefore imperative. This study is a part of a larger project where the long-term goal ... -
CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in Lactobacillus plantarum.
Myrbråten, Ine Storaker; Wiull, Kamilla; Salehian, Zhian; Håvarstein, Leiv Sigve; Straume, Daniel; Mathiesen, Geir; Kjos, Morten (Journal article; Peer reviewed, 2019) -
Display of a β-mannanase and a chitosanase on the cell surface of Lactobacillus plantarum towards the development of whole-cell biocatalysts
Nguyen, H-M; Mathiesen, Geir; Stelzer, Elena Maria; Pham, Mai Lan; Kuczkowska, Katarzyna; Mackenzie, Alasdair; Wittrup_Agger, Jane; Eijsink, Vincentius Gerardus Henricus; Yamabhai, Montarop; Peterbauer, Clemens; Haltrich, Dietmar; Nguyen, T-H (Journal article; Peer reviewed, 2016) -
Display of recombinant proteins at the surface of Lactic Acid Bacteria: strategies and applications
Michon, C; Langella, P; Eijsink, Vincent; Mathiesen, Geir; Chatel, JM (Journal article; Peer reviewed, 2016) -
Expression of endoglucanases in Pichia pastoris under control of the GAP promoter
Varnai, Aniko; Tang, Campbell; Bengtsson, Oskar; Atterton, Andrew; Mathiesen, Geir; Eijsink, Vincent (Journal article; Peer reviewed, 2014) -
Heterologous expression of a recombinant lactobacillal β-galactosidase in Lactobacillus plantarum: effect of different parameters on the sakacin P-based expression system
Nguyen, TT; Nguyen, H-M; Mathiesen, Geir; Eijsink, Vincent; Peterbauer, CK; Haltrich, Dietmar; Nguyen, T-H (Journal article; Peer reviewed, 2015) -
Heterologous protein secretion in lactobacilli with modified pSIP vectors
Maudal, Kristina; Axelsson, Lars; Rud, ida; Eijsink, Vincent; Mathiesen, Geir; Karlskås, Ingrid Lea (Journal article; Peer reviewed, 2014) -
Identification of RseP as a receptor for hybrid bacteriocin H1 in emerging pathogen Staphylococcus haemolyticus
Bartkiewicz, Karolina Teresa (Master thesis, 2020)Staphylococcus haemolyticus is an emerging pathogen which may transfer multi-drug resistance genes to highly virulent Staphylococcus species. S. haemolyticus is a biofilm-producing bacterium and one of the most frequent ... -
Implementation of a two-plasmid CRISPR/Cas9 system in Lactobacillus plantarum : a new approach in the development of a novel vaccine against Mycobacterium tuberculosis
Wiull, Kamilla (Master thesis, 2018)Tuberculosis (TB) is the leading cause of deaths from a single infectious agent, and in 2017 1.7 million people died from TB. To date the only available vaccine against the disease is the bacille Calmette-Guèrin (BCG) ... -
Lactobacillus plantarum displaying CCL3 chemokine in fusion with HIV-1 Gag derived antigen causes increased recruitment of T cells
Kuczkowska, Katarzyna; Mathiesen, Geir; Eijsink, Vincent; Øynebråten, Inger (Journal article; Peer reviewed, 2015) -
Lactobacillus plantarum producing a Chlamydia trachomatis antigen induces a specific IgA response after mucosal booster immunization
Kuczkowska, Katarzyna; Myrbråten, Ine; Øverland, Lise; Eijsink, Vincentius Gerardus Henricus; Follmann, F; Mathiesen, Geir; Dietrich, J (Journal article; Peer reviewed, 2017) -
Over 2000-Fold Increased Production of the Leaderless Bacteriocin Garvicin KS by Increasing Gene Dose and Optimization of Culture Conditions
Telke, Amar; Ovchinnikov, Kirill; Vuoristo, Kiira; Mathiesen, Geir; Thorstensen, Tage; Diep, Dzung B. (Journal article; Peer reviewed, 2019)The leaderless bacteriocin Garvicin KS (GarKS) is a potent antimicrobial, being active against a wide range of important pathogens. GarKS production by the native producer Lactococcus garvieae KS1546 is, however, relatively ... -
Production of potential immune modulating proteins from Methylococcus capsulatus Bath and characterization of their putative roles in inflammation
Aaen, Kristin Hovden (Master thesis, 2019)Commensal microbes have for a long time been considered important for the function and development of the human immune system. Later studies also highlight the beneficial potential of non-commensals to human health. The ... -
Proteomic investigation of the response of Enterococcus faecalis V583 when cultivated in urine
Arntzen, Magnus Øverlie; Karlskås, Ingrid Lea; Skaugen, Morten; Eijsink, Vincent; Mathiesen, Geir (Journal article; Peer reviewed, 2015) -
Secretion and anchoring of a cancer antigen in Lactobacillus plantarum
Flatin, Bjørnar Tovson Bae (Master thesis, 2017)Melanoma is one of the most lethal forms of skin cancer, and immunotherapy continues to be a hot topic for the treatment of this disease. This study is part of a larger project with the long-term goal to develop mucosal ... -
Secretory production of a beta-mannanase and a chitosanase using a Lactobacillus plantarum expression system
Sak-Ubol, S; Namvijitr, P; Pechsrichuang, P; Haltrich, Dietmar; Nguyen, T-H; Mathiesen, Geir; Eijsink, Vincent; Yamabhai, M (Journal article; Peer reviewed, 2016)