Browsing Brage NMBU by Author "Mathiesen, Geir"
Now showing items 1-20 of 46
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A bacteriocin-based treatment option for Staphylococcus haemolyticus biofilms
Kranjec, Christian; Kristensen, Sofie S.; Bartkiewicz, Karolina T.; Brønner, Mikkel; Cavanagh, Jorunn P.; Srikantam, Aparna; Mathiesen, Geir; Diep, Dzung B. (Peer reviewed; Journal article, 2021) -
Anchoring of invasin on the surface of Lactiplantibacillus plantarum exploiting homologous N-terminal transmembrane proteins
Ljosland, Anna Bakke (Master thesis, 2021)Lactic acid bacteria (LAB) are widely used by humans for food production and preservation, and many LAB are natural inhabitants of the human gastrointestinal tract (GIT). For these reasons, LAB are generally recognized as ... -
Ankring av Chlamydia trachomatis antigener på overflaten av Lactobacillus plantarum
Myrbråten, Ine (Master thesis, 2016-11-17)Dette studiet er en del av et større prosjekt der det langsiktige målet er å utvikle slimhinnevaksiner med melkesyrebakterier som leveringsvektorer. Melkesyrebakterier ansees som gode kandidater til dette formål, da de ... -
Biochemical characterization of two cellobiose 2-epimerases and application for efficient production of lactulose and epilactose
Jameson, John-Kristian; Mathiesen, Geir; Pope, Phillip; Westereng, Bjørge; Leanti La Rosa, Sabina (Journal article, 2021) -
Cell Wall Anchoring of a Bacterial Chitosanase in Lactobacillus plantarum Using a Food-Grade Expression System and Two Versions of an LP TG Anchor
Pham, ML; Tran, AM; Mathiesen, Geir; Nguyen, HM; Nguyen, TH (Peer reviewed; Journal article, 2020) -
Celleveggankring av Mycobacterium tuberculosis-antigener på overflaten til Lactobacillus plantarum
Berggreen, Hanne (Master thesis, 2020)Denne oppgaven er en del av et større forskningsprosjekt hvor det langsiktige målet er å utvikle en slimhinnevaksine mot tuberkulose, hvor melkesyrebakterier benyttes som leveringsvektor av antigener. Melkesyrebakterier ... -
Comparison of eight Lactobacillus species for delivery of surface-displayed mycobacterial antigen
Kuczkowska, Katarzyna; Øverland, Lise; Cardoso Da Rocha, Sergio Domingos; Eijsink, Vincent; Mathiesen, Geir (Journal article; Peer reviewed, 2019)Lactobacillus spp. comprise a large group of Gram-positive lactic acid bacteria with varying physiological, ecological and immunomodulatory properties that are widely exploited by mankind, primarily in food production and ... -
Computational and Experimental Analysis of the Secretome of Methylococcus capsulatus (Bath)
Indrelid, Stine; Mathiesen, Geir; Jacobsen, Morten; Lea, Tor Erling; Kleiveland, Charlotte Ramstad (Journal article; Peer reviewed, 2014) -
Constitutive expression and anchoring of Mycobacterium tuberculosis antigens in Lactobacillus plantarum
Wiig, Solveig Birkedal (Master thesis, 2020)Tuberculosis is the leading cause of death caused by a single agent worldwide. A new and effective vaccine against this infection is therefore imperative. This study is a part of a larger project where the long-term goal ... -
CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in Lactobacillus plantarum.
Myrbråten, Ine Storaker; Wiull, Kamilla; Salehian, Zhian; Håvarstein, Leiv Sigve; Straume, Daniel; Mathiesen, Geir; Kjos, Morten (Journal article; Peer reviewed, 2019) -
CRISPR-mediated human germline editing : benefits, risks, and why a ban is unethical
Solvang, Gjertrud Marie (Master thesis, 2021)CRISPR/Cas gene technology provides a versatile system for site-specific gene editing in virtually any cell and has made it possible to cure and prevent genetic diseases and defects. Many genetic diseases, such as Tay Sachs ... -
Developing Lactiplantibacillus as a delivery vehicle for medicinal proteins
Wiull, Kamilla (PhD Thesis;2024:39, Doctoral thesis, 2024)Microbial vaccine vehicles have the potential to become the cheapest and safest option for vaccination due to needle-free administration, and easy production, storage, and distribution. Utilization of non-pathogenic food ... -
Development of a CRISPR/Cas9 editing system for antigen knock-in in Lactiplantibacillus plantarum WCFS1
Haugen, Lisa Kaasbøll (Master thesis, 2022)Lactic acid bacteria (LAB) have been used in food products for hundreds of years and are commonly used in food fermentation, therapeutics, and for health promotion. They are “Generally Recognized as Safe”, have excellent ... -
Development of a non-GMO mucosal vaccine against SARS-CoV-2
Borge, Steffen (Master thesis, 2022)Lactic acid bacteria (LAB) have been proposed as a good delivery vector of surface-bound antigens, in the development of non-genetically modified organism (non-GMO) mucosal vaccines. LABs are considered good because they ... -
Display of a β-mannanase and a chitosanase on the cell surface of Lactobacillus plantarum towards the development of whole-cell biocatalysts
Nguyen, H-M; Mathiesen, Geir; Stelzer, Elena Maria; Pham, Mai Lan; Kuczkowska, Katarzyna; Mackenzie, Alasdair; Wittrup_Agger, Jane; Eijsink, Vincentius Gerardus Henricus; Yamabhai, Montarop; Peterbauer, Clemens; Haltrich, Dietmar; Nguyen, T-H (Journal article; Peer reviewed, 2016) -
Display of recombinant proteins at the surface of Lactic Acid Bacteria: strategies and applications
Michon, C; Langella, P; Eijsink, Vincent; Mathiesen, Geir; Chatel, JM (Journal article; Peer reviewed, 2016) -
Expression and production of thermophilic alginate lyases in Bacillus and direct application of culture supernatant for seaweed saccharification
Rhein-Knudsen, Nanna; Guan, Chengran; Mathiesen, Geir; Horn, Svein Jarle (Peer reviewed; Journal article, 2021)Brown seaweeds are rich in carbohydrates and may be used as a source of fermentable sugars. Saccharification of the seaweed biomass can be carried out enzymatically by a combination of cellulases and alginate lyases. In ... -
Expression of endoglucanases in Pichia pastoris under control of the GAP promoter
Varnai, Aniko; Tang, Campbell; Bengtsson, Oskar; Atterton, Andrew; Mathiesen, Geir; Eijsink, Vincent (Journal article; Peer reviewed, 2014) -
Heterologous expression of a recombinant lactobacillal β-galactosidase in Lactobacillus plantarum: effect of different parameters on the sakacin P-based expression system
Nguyen, TT; Nguyen, H-M; Mathiesen, Geir; Eijsink, Vincent; Peterbauer, CK; Haltrich, Dietmar; Nguyen, T-H (Journal article; Peer reviewed, 2015) -
Heterologous protein secretion in lactobacilli with modified pSIP vectors
Maudal, Kristina; Axelsson, Lars; Rud, ida; Eijsink, Vincent; Mathiesen, Geir; Karlskås, Ingrid Lea (Journal article; Peer reviewed, 2014)