Browsing Brage NMBU by Author "Malik, Muhammad Salman"
Now showing items 1-8 of 8
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Cellular heterogeneity in red and melanized focal muscle changes in farmed Atlantic salmon (Salmo salar) visualized by spatial transcriptomics
Bjørgen, Håvard; Malik, Muhammad Salman; Rimstad, Espen; Vaadal, Marianne; Nyman, Ingvild Berg; Koppang, Erling Olaf; Tengs, Torstein (Peer reviewed; Journal article, 2023)Spatial transcriptomics is a technique that provides insight into gene expression profiles in tissue sections while retaining structural information. We have employed this method to study the pathological conditions related ... -
Dissemination of Piscine orthoreovirus-1 (PRV-1) in Atlantic Salmon (Salmo salar) during the Early and Regenerating Phases of Infection
Kannimuthu, Dhamotharan; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Peer reviewed; Journal article, 2020) -
Dissemination of piscine orthoreovirus-1 (PRV-1) in atlantic salmon (salmo salar) during the early and regenerating phases of infection
Kannimuthu, Dhamotharan; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria K.; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Peer reviewed; Journal article, 2020)Piscine orthoreovirus-1 (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar), but the line of events from infection, pathologic change, and regeneration has not been ... -
Erythroid Progenitor Cells in Atlantic Salmon (Salmo salar) May Be Persistently and Productively Infected with Piscine Orthoreovirus (PRV)
Malik, Muhammad Salman; Bjørgen, Håvard; Kannimuthu, Dhamotharan; Wessel, Øystein; Koppang, Erling Olaf; Di Cicco, Emiliano; Hansen, Elisabeth Furuseth; Dahle, Maria; Rimstad, Espen (Peer reviewed; Journal article, 2019)Piscine orthoreovirus (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus targets erythrocytes in the acute peak phase, followed by cardiomyocytes, before the ... -
Erythroid Progenitor Cells in Atlantic Salmon (Salmo salar) May Be Persistently and Productively Infected with Piscine Orthoreovirus (PRV)
Malik, Muhammad Salman; Bjørgen, Håvard; Kannimuthu, Dhamotharan; Wessel, Øystein; Koppang, Erling Olaf; Di Cicco, Emiliano; Hansen, Elisabeth Furuseth; Dahle, Maria K; Rimstad, Espen (Journal article; Peer reviewed, 2019)Piscine orthoreovirus (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus targets erythrocytes in the acute peak phase, followed by cardiomyocytes, before the ... -
Persistent infection of Piscine orthoreovirus-1 (PRV-1) in Atlantic salmon (Salmo salar)
Malik, Muhammad Salman (PhD thesis;2021:49, Doctoral thesis, 2021)This thesis focuses on infection kinetics, infected cell types, viral shedding, and specific immune responses in persistently Piscine orthoreovirus-1 (PRV-1) infected Atlantic salmon. The aim is to enhance the understanding ... -
Piscine Orthoreovirus (PRV)-3, but Not PRV-2, Cross-Protects against PRV-1 and Heart and Skeletal Muscle Inflammation in Atlantic Salmon
Malik, Muhammad Salman; Teige, Lena Hammerlund; Braaen, Stine; Olsen, Anne Berit; Nordberg, Monica; Amundsen, Marit; Kannimuthu, Dhamotharan; Svenning, Steingrim; Edholm, Eva-Stina Isabella; Takano, Tomokazu; Jørgensen, Jorunn; Wessel, Øystein; Rimstad, Espen; Dahle, Maria (Peer reviewed; Journal article, 2021)Heart and skeletal muscle inflammation (HSMI), caused by infection with Piscine orthoreovirus-1 (PRV-1), is a common disease in farmed Atlantic salmon (Salmo salar). Both an inactivated whole virus vaccine and a DNA vaccine ... -
PRV-1 Infected Macrophages in Melanized Focal Changes in White Muscle of Atlantic Salmon (Salmo salar) Correlates With a Pro-Inflammatory Environment
Malik, Muhammad Salman; Bjørgen, Håvard; Nyman, Ingvild Berg; Wessel, Øystein; Koppang, Erling Olaf; Dahle, Maria; Rimstad, Espen (Peer reviewed; Journal article, 2021)