Blar i Brage NMBU på forfatter "Lindbäck, Toril"
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A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD
Alseth, Ingrun; Rognes, Torbjørn; Lindbäck, Toril; Solberg, Inger; Robertsen, Kristin; Kristiansen, Knut Ivan; Mainieri, Davide; Lillehagen, Lucy; Kolstø, Anne-Brit; Bjørås, M. (Journal article; Peer reviewed, 2006)Soil bacteria are heavily exposed to environmental methylating agents such as methylchloride and may have special requirements for repair of alkylation damage on DNA. We have used functional complementation of an Escherichia ... -
Analyse av Bacillus licheniformis sporegerminering og dens vekstegenskaper under forhold som er relevant for produksjonskjeden av halvfaste oster
Olsen, Linn Renate (Master thesis, 2022)Den sporedannende bakterien Bacillus licheniformis er funnet i modnet ost med kvalitetsforringelser, som gassdannelse og sprekker. Kvalitetsdefekter i ost forårsaket av sporedannende bakterier er et kjent problem (Walstra ... -
Biochemical and mutational analysis of spore cortex-lytic enzymes in the food spoiler Bacillus licheniformis
Aspholm, Marina; Kollerud, Kristian K; Høgberg Hansen, Helge C; Granum, Per Einar; Christie, Graham; Lindbäck, Toril (Journal article; Peer reviewed, 2019)Bacillus licheniformis is frequently associated with food spoilage due to its ability to form highly resistant endospores. The present study reveals that B. licheniformis spore peptidoglycan shares a similar structure to ... -
Commensal E. coli Stx2 lysogens produce high levels of phages after spontaneous prophage induction.
Iversen, Hildegunn; L'Abee-Lund, Trine Marie; Aspholm, Marina; Arnesen, Lotte Pia Stenfors; Lindbäck, Toril (Journal article; Peer reviewed, 2015) -
Culture dependent and independent analyses suggest a low level of sharing of endospore-forming species between mothers and their children
Avershina, Ekaterina; Larsen, Marte Gro; Aspholm, Marina Elisabeth; Lindbäck, Toril; Storrø, Ola; Øien, Torbjørn; Johnsen, Roar; Rudi, Knut (Peer reviewed; Journal article, 2020)Spore forming bacteria comprise a large part of the human gut microbiota. However, study of the endospores in gut microbiota is limited due to difficulties of culturing and numerous unknown germination factors. In this ... -
The effects of vitamin K on enterohemorrhagic Escherichia coli
Kijewski, Anne Cecilie Riihonen (PhD thesis;2024:24, Doctoral thesis, 2024)Enterohemorrhagic Escherichia coli (EHEC) is the cause of foodborne outbreaks, hospitalizations, and deaths worldwide. Today, no optimal treatment for EHEC infections exist, as antibiotics may increase production of Shiga ... -
Endospore Appendages: a novel pilus superfamily from the endospores of pathogenic Bacilli
Pradhan, Brajabandhu; Liedtke, Janine; Sleutel, Mike; Lindbäck, Toril; Zegeye, Ephrem Debebe; O_Sullivan, Kristin; Llarena, Ann-Katrin; Brynildsrud, Ola Brønstad; Aspholm, Marina Elisabeth; Remaut, Han (Peer reviewed; Journal article, 2021)Bacillus cereus sensu lato is a group of Gram-positive endospore-forming bacteria with high ecological diversity. Their endospores are decorated with micrometer-long appendages of unknown identity and function. Here, we ... -
Enterohaemorrhagic E. coli O103:H25 modulates expression of LEE-encoded virulence genes in response to direct cell-cell contact with the gut commensal Bacteroides thetaiotaomicron
Kijewski, Anne Cecilie Riihonen (Master thesis, 2015-08-03)Enterohemorrhagic Escherichia coli (EHEC) is a foodborne pathogen of the colon that causes disease with varying severity. Symptoms range from mild diarrhea to hemolytic uremic syndrome (HUS), which at worst can be fatal. ... -
Environmental risk assessment of the genetically modified vaccine Recombitek®C4
Sipinen, Ville Erling; Rimstad, Espen; Brinchmann, Jan Engelsen; Frostegård, Åsa; Tønnessen, Ragnhild; Blix, Hege Salvesen; Gjøen, Tor; Lindbäck, Toril; Melby, Kjetil Klaveness (Report, 2025)Det er ikke høyere miljørisiko ved bruk av den genmodifiserte vaksinen Recombitek®C4 enn ved bruk av tilsvarende godkjente vaksiner. Det er hovedbudskapet i en risikovurdering VKM har gjort for Miljødirektoratet. Bakgrunn ... -
Functional characterization of the germination receptors in the spore-forming species Bacillus licheniformis
Borch-Pedersen, Kristina (PhD Thesis;2017:80, Doctoral thesis, 2017)The food industry experience extensive losses worldwide due to food spoilage caused by microbial activity. Endospore-forming bacteria, such as members of the genera Bacillus and Clostridium, are becoming increasingly ... -
High diversity in the regulatory region of Shiga toxin encoding bacteriophages
Fagerlund, Annette; Aspholm, Marina; Wegrzyn, Grzegorz; Lindbäck, Toril (Peer reviewed; Journal article, 2022)Background: Enterohemorrhagic Escherichia coli (EHEC) is an emerging health challenge worldwide and outbreaks caused by this pathogen poses a serious public health concern. Shiga toxin (Stx) is the major virulence factor ... -
Microbial interactions : effects on virulence in Enterohaemorrhagic Escherichia coli (EHEC)
Iversen, Hildegunn (PhD Thesis;2015:51, Doctoral thesis, 2017-07-13)Enterohaemorrhagic Escherichia coli (EHEC) is an emerging food borne pathogen associated with a number of outbreaks worldwide, and is a serious public health threat. The symptoms of the disease can range from mild diarrhoea ... -
MogR is a ubiquitous transcriptional repressor affecting motility, biofilm formation and virulence in Bacillus thuringiensis
Smith, Veronika; Josefsen, Malin; Lindbäck, Toril; Hegna, Ida Kristin; Finke, Sarah; Tourasse, Nicolas Jacques; Nielsen-LeRoux, Christina; Økstad, Ole Andreas; Fagerlund, Annette (Journal article; Peer reviewed, 2020-12)Flagellar motility is considered an important virulence factor in different pathogenic bacteria. In Listeria monocytogenes the transcriptional repressor MogR regulates motility in a temperature-dependent manner, directly ... -
Norwegian raw cow`s milk, a potential source of zoonotic pathogens?
Idland, Lene (PhD Thesis;2022:71, Doctoral thesis, 2023)The worldwide emerging trend of eating “natural” foods, that has not been processed, also applies for beverages. According to Norwegian legislation, all milk must be pasteurized before commercial sale but drinking milk ... -
Replication Region Analysis Reveals Non-lambdoid Shiga Toxin Converting Bacteriophages
Llarena, Ann-Katrin; Aspholm, Marina Elisabeth; O_Sullivan, Kristin; Wêgrzyn, Grzegorz; Lindbäck, Toril (Peer reviewed; Journal article, 2021)Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages). Numerous Stx phages have been ... -
The effect of high pressure on Bacillus licheniformis spore germination and inactivation
Borch-Pedersen, Kristina; Mellegård, Hilde; Boysen, Preben; Reineke, Kai; Sevenich, Robert; Lindbäck, Toril; Aspholm, Marina (Journal article; Peer reviewed, 2017) -
The gut bacterium Bacteroides thetaiotaomicron influences the virulence potential of the enterohemorrhagic Escherichia coli 0103:H25
Iversen, Hildegunn; Lindbäck, Toril; L'Abee-Lund, Trine Marie; Roos, Norbert; Aspholm, Marina; Arnesen, Lotte Pia Stenfors (Journal article; Peer reviewed, 2015) -
Vitamin K analogs influence the growth and virulence potential of enterohemorrhagic Escherichia coli
Kijewski, Anne Cecilie Riihonen; Witsø, Ingun Lund; Iversen, Hildegunn; Rønning, Helene Thorsen; Normann, Trine Marie; Wasteson, Yngvild; Lindbäck, Toril; Aspholm, Marina (Peer reviewed; Journal article, 2020) -
Whole-Genome Sequencing Analysis of Listeria monocytogenes from Rural, Urban, and Farm Environments in Norway: Genetic Diversity, Persistence, and Relation to Clinical and Food Isolates
Fagerlund, Annette; Idland, Lene; Heir, Even; Møretrø, Trond; Aspholm, Marina Elisabeth; Lindbäck, Toril; Langsrud, Solveig (Peer reviewed; Journal article, 2022)Listeria monocytogenes is a ubiquitous environmental bacterium associated with a wide variety of natural and human-made environments, such as soil, vegetation, livestock, food processing environments, and urban areas. It ...