Blar i Brage NMBU på forfatter "Lea, Tor Erling"
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An in vitro model for determining the chemo-sensitizing effects of hyperthermia on ovarian cancer cell lines
Herud, Morten Theodor Malmer (Master thesis, 2017)Ovarian cancers, the deadliest of gynecological malignancies, claim the lives of 300 Norwegian women every year. The disease is characterized by late stage detection and the majority of patients present peritoneal metastases ... -
Ancestral wheat types release fewer celiac disease related t cell epitopes than common wheat upon ex vivo human gastrointestinal digestion
Asledottir, Tora; Rehman, Rashida; Mamone, Gianfranco; Picariello, Gianluca; Devold, Tove Gulbrandsen; Vegarud, Gerd Elisabeth; Røseth, Arne; Lea, Tor Erling; Halstensen, Trond S.; Ferranti, Pasquale; Uhlen, Anne Kjersti (Peer reviewed; Journal article, 2020) -
Computational and Experimental Analysis of the Secretome of Methylococcus capsulatus (Bath)
Indrelid, Stine; Mathiesen, Geir; Jacobsen, Morten; Lea, Tor Erling; Kleiveland, Charlotte Ramstad (Journal article; Peer reviewed, 2014) -
Effekt av antioksidanttilskudd på muskulære tilpasninger til utholdenhetstrening : Western blot analyser av COX4 og HSP60 fra m.vastus lateralis
Buer, Charlotte (Master thesis, 2012-09-07)Bakgrunn: Produsenter av antioksidanttilskudd har lenge hevdet at toppidrettsutøvere bør ta slike tilskudd for å bedre prestasjon, samt å øke helsegevinstene i forbindelse med utholdenhetstrening. De underliggende mekanismene ... -
Egenskaper til in silico-identifiserte bioaktive peptider fra erteprotein i to ulike modeller av Caco-2 adenokarsinomceller
Holmemo, Carina Wiker (Master thesis, 2020)Bakgrunn: Som en del av forskningsprosjektet FoodProFuture er det ønsket å undersøke mulige helseeffekter som ulike komponenter i proteinrike matplanter kan ha. Etter in vitro- fordøyelse av ertemel ble en rekke peptider ... -
Establishment and characterization of a gatekeeper mutation for protein kinase D1 and 3
Isaksen, Maria Xepapadakis (Master thesis, 2016-09-07)Protein kinase D constitutes a novel family of Ser/Thr specific kinases and contains three members; PKD1-3. This protein kinase family has been described to carry out different functions and responses at various locations ... -
Investigating The Role of FOXO1 in the Differentiation of Mesenchymal Stem Cells towards Chondrodytes
Al-Modawi, Rua Nader (Master thesis, 2012-10-15)Human mesenchymal stem cells (MSCs) have a profound potential in regenerative medicine. MSCs ability to differentiate into various tissue types in vitro provides a promising approach to tissue engineering and subsequently ... -
Investigation of the WNT and AKT/mTOR signaling pathways in early differentiation in embryonic stem cells
Aslaksen, Sigrid (Master thesis, 2016-07-27)Embryonic stem cells have a huge potential in the field of tissue engineering, biomedical research and regenerative medicine as they possess the capacity to generate every type of cell and tissue in the body. The ability ... -
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism
Jensen, Benjamin Anderschou Holbech; Holm, Jacob B.; Larsen, Ida S.; von Burg, Nicole; Derer, Stefanie; Sonne, Si B.; Pærrgaard, Simone I.; Damgaard, Mads V.; Indrelid, Stine Hufthammer; Rivollier, Aymeric; Agrinier, Anne-Laure; Sulek, Karolina; Arnoldussen, Yke Jildouw; Fjære, Even; Marette, André; Angell, Inga Leena; Rudi, Knut; Treebak, Jonas Thue; Madsen, Lise; Åkesson, Caroline Piercey; Agace, William; Sina, Christian; Kleiveland, Charlotte Ramstad; Kristiansen, Karsten; Lea, Tor Erling (Peer reviewed; Journal article, 2021)Interactions between host and gut microbial communities are modulated by diets and play pivotal roles in immunological homeostasis and health. We show that exchanging the protein source in a high fat, high sugar, westernized ... -
Production of potential immune modulating proteins from Methylococcus capsulatus Bath and characterization of their putative roles in inflammation
Aaen, Kristin Hovden (Master thesis, 2019)Commensal microbes have for a long time been considered important for the function and development of the human immune system. Later studies also highlight the beneficial potential of non-commensals to human health. The ... -
The mycotoxin alternariol induces DNA damage and modify macrophage phenotype and inflammatory responses
Solhaug, Anita; Wisbech, Cathrine; Christoffersen, Trine Eker; Hult, Lene Therese Olsen; Lea, Tor Erling; Eriksen, Gunnar Sundstøl; Holme, Jørn Andreas (Journal article; Peer reviewed, 2015) -
The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer
Paulsen, Ørnulf; Laird, Barry J; Aass, Nina Kathrine; Lea, Tor Erling; Fayers, Peter; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2017) -
The soil bacterium Methylococcus capsulatus bath interacts with human dendritic cells to modulate immune function
Indrelid, Stine Anita; Kleiveland, Charlotte Ramstad; Holst, René; Jacobsen, Morten; Lea, Tor Erling (Journal article; Peer reviewed, 2017) -
β-catenin do not localize with WNT destruction complex components in tankyrase inhibitor resistant HCT-15 colorectal cancer cells
Melheim, Maria (Master thesis, 2017)Blant kaskader og signalveier i cellene har feil i WNT signalveien vist å ha stor betydning i kreftutvikling. I friske celler bytter signalveien på å være aktiv og inaktiv og regulerer på denne måten ulike systemer i ...