Browsing Brage NMBU by Author "Harvey, Thomas Nelson"
Now showing items 1-12 of 12
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Assessment of fatty acid desaturase (Fads2) structure-function properties in fish in the context of environmental adaptations and as a target for genetic engineering
Bláhová, Zuzana; Harvey, Thomas Nelson; Pšenička, Martin; Mráz, Jan (Peer reviewed; Journal article, 2020)Fatty acid desaturase 2 (Fads2) is the key enzyme of long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis. Endogenous production of these biomolecules in vertebrates, if present, is insufficient to meet demand. ... -
Cloning and characterization of Cas9 in IPEC-J2 cells for CRISPR screens against porcine E. coli pathogen
Arntsen, Jostein (Master thesis, 2021)Bakgrunn Svin er ofte brukt husdyr i landbruket, brukt primært for dets kjøtt. Et ofte forekommende problem i svineindustrien er diare forårsaket av bakterier, hvor enterotoksinproduserende Escherichia coli(ETEC) er en ... -
Comparative transcriptomics reveals domestication‐associated features of Atlantic salmon lipid metabolism
Jin, Yang; Olsen, Rolf Erik; Harvey, Thomas Nelson; Østensen, Mari-Ann; Li, Keshuai; Santi, Nina; Vadstein, Olav; Bones, Atle M.; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Peer reviewed; Journal article, 2020) -
Comparative transcriptomics reveals domestication‐associated features of Atlantic salmon lipid metabolism
Jin, Yang; Olsen, Rolf Erik; Harvey, Thomas Nelson; Østensen, Mari-Ann; Li, Keshuai; Santi, Nina; Vadstein, Olav; Bones, Atle M.; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Peer reviewed; Journal article, 2020) -
Developing Cas9 expressing MDBK cell lines for GeCKO screening against bovine diseases
Nalpadan, Avon Augustin (Master thesis, 2022)Cas9 expressing MDBK (Madin-Darby bovine kidney) cell lines were produced for a GeCKO (genome scale CRISPR/Cas9 gene knockout) screening against Bovine diseases. The lines were transduced with lentiviral vectors containing ... -
Development of lentiviral technology for use in Atlantic salmon
Andreassen, Sara Stenmark (Master thesis, 2022)Lentiviral vectors are used to deliver and stably integrate genetic material into the genome of cells. When combined with CRISPR based gene editing technology, targeted editing of one or many host genes in a pooled format ... -
Diet and Life Stage-Associated Lipidome Remodeling in Atlantic Salmon
Jin, Yang; Harvey, Thomas Nelson; Bartosova, Zdenka; Hassani, Sahar; Bruheim, Per; Sandve, Simen Rød; Vik, Jon Olav (Peer reviewed; Journal article, 2021) -
Genomic regions and signaling pathways associated with indicator traits for feed efficiency in Atlantic salmon (Salmo salar)
Dvergedal, Hanne; Harvey, Thomas Nelson; Jin, Yang; Ødegård, Jørgen; Grønvold, Lars; Sandve, Simen Rød; Våge, Dag Inge; Moen, Thomas; Klemetsdal, Gunnar (Peer reviewed; Journal article, 2020) -
Life-stage associated remodeling of lipid metabolism regulation in Atlantic salmon
Gillard, Gareth Benjamin; Harvey, Thomas Nelson; Gjuvsland, Arne Bjørke; Jin, Yang; Thomassen, Magny Sissel S.; Lien, Sigbjørn; Leaver, Michael; Torgersen, Jacob Seilø; Hvidsten, Torgeir Rhoden; Vik, Jon Olav; Sandve, Simen Rød (Journal article; Peer reviewed, 2018) -
Liver slice culture as a model for lipid metabolism in fish
Harvey, Thomas Nelson; Sandve, Simen Rød; Jin, Yang; Vik, Jon Olav; Torgersen, Jacob Seilø (Peer reviewed; Journal article, 2019) -
Pseudotyping lentiviral vectors for transduction of Salmo salar cells using glycoprotein from infectious salmon anaemia virus
Låstad, Thea Marie (Master thesis, 2023)Lentivirus is commonly used as vector for CRISPR applications. The common vector system utilises glycoproteins from the vesicular stomatitis virus (VSV-G). This vector has broad a tropism, including the salmonid species ... -
Transcriptional regulation of lipid metabolism when salmon fry switches from endogenous to exogenous feeding
Jin, Yang; Olsen, Rolf Erik; Østensen, Mari-Ann; Gillard, Gareth Benjamin; Li, Keshuai; Harvey, Thomas Nelson; Santi, Nina; Vadstein, Olav; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)