Browsing Brage NMBU by Author "Espenes, Arild"
Now showing items 1-17 of 17
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Activation of innate immune genes in caprine blood leukocytes after systemic endotoxin challenge
Heegaard, Peter M.H.; Tranulis, Michael A.; Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Ersdal, Cecilie; Skovgaard, Kerstin (Journal article; Peer reviewed, 2016) -
Cell and context-dependent sorting of neuropathy-associated protein NDRG1 - Insights from canine tissues and primary Schwann cell cultures
Skedsmo, Fredrik Strebel; Tranulis, Michael A.; Espenes, Arild; Prydz, Kristian; Matiasek, Kaspar; Gunnes, Gjermund; Hermansen, Lene Cecilie; Jäderlund, Karin Hultin (Journal article; Peer reviewed, 2019) -
Demyelinating polyneuropathy in goats lacking prion protein.
Skedsmo, Fredrik Strebel; Malachin, Giulia; Våge, Dag Inge; Hammervold, Mie Marie; Salvesen, Øyvind; Ersdal, Cecilie; Ranheim, Birgit; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Bruheim, Per; Jäderlund, Karin Hultin; Matiasek, Kaspar; Espenes, Arild; Tranulis, Michael A. (Peer reviewed; Journal article, 2019)Studies in mice with ablation of Prnp, the gene that encodes the cellular prion protein (PrPC), have led to the hypothesis that PrPC is important for peripheral nerve myelin maintenance. Here, we have used a nontransgenic ... -
Goats naturally devoid of PrPC are resistant to scrapie
Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020)Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the “protein-only” hypothesis, the normal host-encoded prion protein (PrPC) is converted into a pathological ... -
Goats naturally devoid of PrPC are resistant to scrapie
Salvesen, Øyvind; Espenes, Arild; Reiten, Malin Rokseth; Vuong, Tram Thu; Malachin, Giulia; Tran, Linh Dinh Thoai; Andréoletti, Olivier; Olsaker, Ingrid; Benestad, Sylvie Lafond; Tranulis, Michael A.; Ersdal, Cecilie (Peer reviewed; Journal article, 2020)Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the "protein-only" hypothesis, the normal host-encoded prion protein (PrPC) is converted into a pathological ... -
Hematological shift in goat kids naturally devoid of prion protein
Reiten, Malin Rokseth; Bakkebø, Maren Kolltveit; Brun-Hansen, Hege; Lewandowska-Sabat, Anna; Olsaker, Ingrid; Tranulis, Michael A.; Espenes, Arild; Boysen, Preben (Journal article; Peer reviewed, 2015) -
Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D
Skedsmo, Fredrik; Espenes, Arild; Tranulis, Michael A.; Matiasek, Kaspar; Gunnes, Gjermund; Bjerkås, Inge; Moe, Lars; Røed, Susan Skogtvedt; Berendt, Mette; Fredholm, Merete; Rohdin, Cecilia; Shelton, G. Diane; Bruheim, Per; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Hermansen, Lene Cecilie; Stigen, Øyvind; Jäderlund, Karin Hultin (Peer reviewed; Journal article, 2021) -
Investigation of the gut-associated lymphoid tissue in sheep with emphasis on natural killer cells
Olsen, Line (PhD Thesis;2015:52, Doctoral thesis, 2017-07-04)The gut-associated lymphoid tissue (GALT) of sheep has been investigated for decades, and several immune cells receding within these structures have been described. The GALT of sheep has specialized compartments described ... -
NDRG1 and PrPC in peripheral nerve myelin maintenance : insights from morphological studies in two unique animal models
Skedsmo, Fredrik Strebel (PhD Thesis;2020:28, Doctoral thesis, 2020)Peripheral nerves transmit signals between peripheral tissue and the central nervous system, essential for normal motor and sensory function. To enable this, the integrity of both the axon and Schwann cell is crucial. The ... -
Non-neuronal functions of the prion protein : insights from a unique animal model
Reiten, Malin Rokseth (PhD Thesis;2017:68, Doctoral thesis, 2017)The physiological function of the cellular prion protein (PrPC) remains enigmatic. A misfolded, infectious conformer of the protein, known as the scrapie isoform PrPSc, is able to aggregate in brain tissue and cause a group ... -
Prion protein in myelin maintenance: What does the goat say?
Skedsmo, Fredrik; Espenes, Arild; Tranulis, Michael A. (Peer reviewed; Journal article, 2021) -
Re-emergence of hereditary polyneuropathy in Scandinavian Alaskan malamute dogs - old enemy or new entity? A case series
Jäderlund, Karin Hultin; Rohdin, Cecilia; Berendt, Mette; Stigen, Øyvind; Fredholm, Merete; Espenes, Arild; Bjerkås, Inge; Moe, Lars (Journal article; Peer reviewed, 2017) -
Stress resilience of spermatozoa and blood mononuclear cells without prion protein
Reiten, Malin Rokseth; Malachin, Giulia; Kommisrud, Elisabeth; Østby, Gunn Charlotte; Waterhouse, Karin Elisabeth; Krogenæs, Anette Kristine; Kusnierczyk, Anna; Bjørås, Magnar; Jalland, Clara Maria Osnes; Nekså, Liv Heidi; Røed, Susan Skogtvedt; Stenseth, Else-Berit; Myromslien, Frøydis Deinboll; Zeremichael, Teklu Tewoldebrhan; Bakkebø, Maren Kolltveit; Espenes, Arild; Tranulis, Michael A. (Journal article; Peer reviewed, 2018) -
The cellular prion protein : a player in immunological quiescence
Bakkebø, Maren Kolltveit; Mouillet-Richard, Sophie; Espenes, Arild; Goldmann, Wilfred; Tatzelt, Joerg; Tranulis, Michael A. (Journal article; Peer reviewed, 2015) -
The cellular prion protein and the inflammatory response
Salvesen, Øyvind (PhD Thesis;2017:81, Doctoral thesis, 2017)The cellular prion protein (PrPC) is known for its pivotal role in the development of prion diseases, such as Creutzfeldt-Jakob disease in humans and scrapie in small ruminants. In these diseases, PrPC is converted into a ... -
The early intestinal immune response in experimental neonatal ovine cryptosporidiosis is characterized by an increased frequency of perforin expressing NCR1+ NK cells and by NCR1− CD8+ cell recruitment
Olsen, Line; Åkesson, Caroline Piercey; Storset, Anne; Lacroix-Lamande, Sonia; Boysen, Preben; Metton, Coralie; Connelley, Timothy; Espenes, Arild; Laurent, Fabrice; Drouet, Francoise (Journal article; Peer reviewed, 2015) -
Yessotoxin triggers ribotoxic stress
Korsnes, Monica Suarez; Røed, Susan Skogtvedt; Tranulis, Michael A.; Espenes, Arild; Christophersen, Berit (Journal article; Peer reviewed, 2014)