Blar i Brage NMBU på forfatter "Carlsen, Harald"
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A transgenic reporter mouse model for in vivo assessment of retinoic acid receptor transcriptional activation
Carlsen, Harald; Ebihara, Kanae; Kuwata, Nobuyo H.; Kuwata, Kazuhisa; Aydemir, Gamze; Rühl, Ralph; Blomhoff, Rune (Peer reviewed; Journal article, 2021) -
Bacteriocins Revitalize Non-Effective Penicillin G to Overcome Methicillin-Resistant Staphylococcus pseudintermedius
Ovchinnikov, Kirill; Kranjec, Christian; Thorstensen, Tage; Carlsen, Harald; Diep, Dzung B. (Peer reviewed; Journal article, 2022)The rise of antibiotic-resistant bacteria is among the biggest challenges in human and veterinary medicine. One of the major factors that contributes to resistance is use of frontline clinical antibiotics in veterinary ... -
Betydningen av NOX1 for utviklingen av metabolsk syndrom i mus fôret med høyfettdiett med og uten favabønner
Hulsund, Sissel Katrine (Master thesis, 2020)Bakgrunn: Metabolsk syndrom er sterkt knyttet til fedme hvor vanligste årsak er høyfettdietter og sedativ livsstil. Fedme fører til lavgradsinflammasjon i fettvev og lever og er pådriver for insulinresistens og MetS. ... -
Calorie and protein restriction in mammals : a review and comparison on respect to aging
Nossen, Johan Noraker (Master thesis, 2016-11-21)Calorie restriction (CR), a 10-50% (typically 30%) reduction in calorie intake with adequate nutrients, is the most widely accepted intervention to delay aging and increase lifespan in many model organisms. Recently, there ... -
Can oral administration of lipopolysaccharide (LPS) exaggerate metabolic effects and inflammation imposed by a Western diet in mice?
Skogen, Vemund Heggen (Master thesis, 2019)A Western diet is an energy dense and nutrient poor diet associated with low-grade inflammatory consequences and is implicated in causing a range of non-communicable diseases (NCDs) including obesity and diabetes type 2 ... -
Coffee intake and the effects on intestinal inflammation, metabolic homeostasis and intestinal barrier function in mice
Harvei, Silje (Master thesis, 2016-09-14)Epidemiological studies have associated coffee consumption with beneficial effects including reduced risk of metabolic diseases such as type 2 diabetes. Conclusive results from experimental studies remain yet to be defined, ... -
Contribution of epigenetic and epitranscriptomic factors in gene regulation of embryonic stem cells : I. Generation of Ythdf1-3 knock-outs and characterization of their phenotypes. II. Investigating the role of a chromatin modifier, MMSET in R-loop biology
Østby, Gina Henriette; Aarseth, Katrine Råkjær (Master thesis, 2020)Both epigenetic and epitranscriptomic modifications have been revealed to impact gene regulation and are linked to numerous diseases and oncogenic reprogramming. Reversible alterations in gene expression with no effects ... -
Dietary influence on intestinal microbiota and immune responses in mice : roles of high-fat diet and reactive oxygen species (ROS)
Rocha, Sérgio Domingos Cardoso da (PhD Thesis;2020:60, Doctoral thesis, 2020)The gastrointestinal tract harbors trillions of bacteria. Host and microbiota co-evolved in a mutualism relationship with a certain degree of dependency, where the host provides a nutrient-rich environment and benefits ... -
Dietary intake of micronized avian eggshell membrane in aged mice reduces circulating inflammatory markers, increases microbiota diversity, and attenuates skeletal muscle aging
Rønning, Sissel Beate; Carlsen, Harald; Rocha, Sergio Domingos Cardoso; Rud, Ida; Solberg, Nina; Høst, Vibeke; Veiseth-Kent, Eva; Arnesen, Henriette; Bergum, Silje; Kirkhus, Bente; Böcker, Ulrike; Abedali, Nada; Rundblad, Amanda; Bålsrud, Pia; Måge, Ingrid; Holven, Kirsten Bjørklund; Ulven, Stine Marie; Pedersen, Mona Elisabeth (Peer reviewed; Journal article, 2024)Introduction: Avian eggshell membrane (ESM) is a complex extracellular matrix comprising collagens, glycoproteins, proteoglycans, and hyaluronic acid. We have previously demonstrated that ESM possesses anti-inflammatory ... -
Effect of an enriched microbial environment on maintenance of gut health and tissue homeostasis in mice
Hindhamar, Linda Kristine (Master thesis, 2020)Introduction: The house mouse, as humans and other animals, have co-evolved with the billions of microbes surrounding them and colonizing their bodies and composing their microbiota. Microbes colonizing the gut, namely the ... -
Effect of calcium on fatty acid digestibility and weight development in mice
Meling, Sebastian (Master thesis, 2021)Background: High intake of saturated fatty acids (SFA) has consistently been shown to raise low-density lipoprotein cholesterol, a known risk factor of cardiovascular disease (CVD). One of the most significant contributors ... -
Effect of different modes of naturalization on expression of barrier-related genes in the murine intestine
Birkeland, Signe (Master thesis, 2022) -
Effects of a diet intervention on plasma lipopolysaccharide-binding protein in colorectal cancer patients
Van der Straeten, Sarah (Master thesis, 2019)Objective: Increased systemic level of lipopolysaccharide-binding protein (LBP) is proposed to be a biomarker of increased gut permeability. The main objective of this master thesis was to investigate whether a one year ... -
The effects of ketogenic diet and fasting on inflammation in mice
Kopperud, Jørgen (Master thesis, 2022) -
Effekt av kalsium på fordøyelse av fettsyrer og uttrykk av gener involvert i kolesterolhomeostase i mus
Uglum, Marte Andréa (Master thesis, 2021)Bakgrunn: Hjerte- og karsykdom (HKS), og særlig aterosklerotisk sykdom, er globalt en stor helsebyrde og er den ledende dødsårsaken i verden. Høye konsentrasjoner av lavtetthet-lipoprotein (LDL) i blodet er assosiert med ... -
Effekt av NOX1 og Reaktive oksygenforbindelser i tarm hos mus som fôres med høyfettdiett
Wesenberg, Eirin Haraldsdotter (Master thesis, 2020)Bakgrunn: Et velfungerende fordøyelsessystem er viktig for både mental og fysisk helse. Særlig er et kontrollert miljø og symbiotisk mikrobiom i nederste del av tynntarm svært viktig, da hovednæringsopptak skjer i dette ... -
Effekter av gluten og fruktaner på fekale inflammatoriske og mikrobiotaassosierte biomarkører hos pasienter med ikke-cøliakisk glutensensitivitet
Aspholm, Trude Elise (Master thesis, 2020)Bakgrunn og målsetning: Årsaken til og patogenesen for gastrointestinale (GI) problemer hos pasienter med ikke-cøliakisk gluten sensitivitet (NCGS) er ukjent, men pasientene opplever bedring i symptomene ved glutenfri ... -
Establishment of a CD4+ naïve T cell cultivation and stimulation protocol for future studies of cellular responses in rheumatoid arthritis
Einertsen, Emilie (Master thesis, 2022)Rheumatoid arthritis (RA) is a complex autoimmune disease that primarily causes inflammation in the synovial membrane of joints in the body. It is a multifactorial disease that involves a combination of genetic, epigenetic, ... -
Evaluation of the leaderless bacteriocins EntEJ97s and EntK1 as novel treatment options against antibiotic resistant enterococci
Bøyum, Ingvild Reinseth (PhD Thesis;2025:19, Doctoral thesis, 2025)The discovery of antibiotics was revolutionary for mankind, but currently the world is presented with a looming antibiotic-resistance crisis. One of the important steps to combat this crisis is to discover new treatment ... -
Exploring the Therapeutic Potenital of the Leaderless Enterocins K1 and EJ97 in the Treatment of Vancomycin-Resistant Enterococcal Infection
Reinseth, Ingvild; Tønnesen, Hanne Hjorth; Carlsen, Harald; Diep, Dzung B. (Journal article; Peer reviewed, 2021)