Blar i Brage NMBU på forfatter "Bjørgen, Håvard"
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Anatomy of teleost fish immune structures and organs
Bjørgen, Håvard; Koppang, Erling Olaf (Peer reviewed; Journal article, 2021)The function of a tissue is determined by its construction and cellular composition. The action of different genes can thus only be understood properly when seen in the context of the environment in which they are expressed ... -
Anatomy, immunology, digestive physiology and microbiota of the salmonid intestine: Knowns and unknowns under the impact of an expanding industrialized production
Bjørgen, Håvard; Li, Yanxian; Kortner, Trond M.; Krogdahl, Åshild; Koppang, Erling Olaf (Peer reviewed; Journal article, 2020)Increased industrialized production of salmonids challenges aspects concerning available feed resources and animal welfare. The immune system plays a key component in this respect. Novel feed ingredients may trigger ... -
Dissemination of Piscine orthoreovirus-1 (PRV-1) in Atlantic Salmon (Salmo salar) during the Early and Regenerating Phases of Infection
Kannimuthu, Dhamotharan; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Peer reviewed; Journal article, 2020) -
Dissemination of piscine orthoreovirus-1 (PRV-1) in atlantic salmon (salmo salar) during the early and regenerating phases of infection
Kannimuthu, Dhamotharan; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria K.; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Peer reviewed; Journal article, 2020)Piscine orthoreovirus-1 (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar), but the line of events from infection, pathologic change, and regeneration has not been ... -
Ectopic epithelial cell clusters in salmonid intestine are associated with inflammation
Bjørgen, Håvard; Koppang, Erling Olaf; Gunnes, Gjermund; Hordvik, Ivar; Moldal, Torfinn; Kaldhusdal, Magne; Dale, Ole Bendik (Journal article; Peer reviewed, 2018) -
Effekten av turbiditet i RAS-anlegg på gjellehelse målt i antall slimceller i gjellene hos atlantisk laks i settefiskproduksjon
Figenschou, Alexander J. Hat.; Hillestad, Linn-Anett (Student paper, others, 2019)I dette studiet ble det studert sammenhengen mellom turbiditet og antall slimceller i gjellene til atlantisk laks. Hypotesen var at høy turbiditet (og dermed lav siktdybde i vannkarene) i RAS-anlegg kan føre til økt mekanisk ... -
Erythroid Progenitor Cells in Atlantic Salmon (Salmo salar) May Be Persistently and Productively Infected with Piscine Orthoreovirus (PRV)
Malik, Muhammad Salman; Bjørgen, Håvard; Kannimuthu, Dhamotharan; Wessel, Øystein; Koppang, Erling Olaf; Di Cicco, Emiliano; Hansen, Elisabeth Furuseth; Dahle, Maria; Rimstad, Espen (Peer reviewed; Journal article, 2019)Piscine orthoreovirus (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus targets erythrocytes in the acute peak phase, followed by cardiomyocytes, before the ... -
Erythroid Progenitor Cells in Atlantic Salmon (Salmo salar) May Be Persistently and Productively Infected with Piscine Orthoreovirus (PRV)
Malik, Muhammad Salman; Bjørgen, Håvard; Kannimuthu, Dhamotharan; Wessel, Øystein; Koppang, Erling Olaf; Di Cicco, Emiliano; Hansen, Elisabeth Furuseth; Dahle, Maria K; Rimstad, Espen (Journal article; Peer reviewed, 2019)Piscine orthoreovirus (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus targets erythrocytes in the acute peak phase, followed by cardiomyocytes, before the ... -
High-Resolution, 3D Imaging of the Zebrafish Gill-Associated Lymphoid Tissue (GIALT) Reveals a Novel Lymphoid Structure, the Amphibranchial Lymphoid Tissue
Dalum, Alf Seljenes; Kraus, Aurora; Khan, Shanawaz; Davydova, Erna; Rigaudeau, Dimitri; Bjørgen, Håvard; Lopez Porras, Adrian; Griffiths, Gareth Wyn; Wiegertjes, Geert F.; Koppang, Erling Olaf; Salinas, Irene; Boudinot, Pierre; Resseguier, Julien (Journal article; Peer reviewed, 2021)The zebrafish is extensively used as an animal model for human and fish diseases. However, our understanding of the structural organization of its immune system remains incomplete, especially the mucosa-associated lymphoid ... -
High-Resolution, 3D Imaging of the Zebrafish Gill-Associated Lymphoid Tissue (GIALT) Reveals a Novel Lymphoid Structure, the Amphibranchial Lymphoid Tissue
Dalum, Alf Seljenes; Kraus, Aurora; Khan, Shanawaz; Davydova, Erna; Rigaudeau, Dimitri; Bjørgen, Håvard; Lopez Porras, Adrian; Griffiths, Gareth Wyn; Wiegertjes, Geert F.; Koppang, Erling Olaf; Salinas, Irene; Boudinot, Pierre; Resseguier, Julien (Journal article; Peer reviewed, 2021)The zebrafish is extensively used as an animal model for human and fish diseases. However, our understanding of the structural organization of its immune system remains incomplete, especially the mucosa-associated lymphoid ... -
IgM+ and IgT+ B Cell Traffic to the Heart during SAV Infection in Atlantic Salmon
Bakke, Anne Flore; Bjørgen, Håvard; Koppang, Erling Olaf; Frost, Petter; Afanasyev, Sergey; Boysen, Preben; Krasnov, Aleksei; Lund, Hege (Peer reviewed; Journal article, 2020)B cells of teleost fish differentiate in the head kidney, and spleen, and either remain in the lymphatic organs or move to the blood and peripheral tissues. There is limited knowledge about piscine B cell traffic to sites ... -
Immunopathological characterization of red focal changes in Atlantic salmon (Salmo salar) white muscle
Bjørgen, Håvard; Kumar, Subramani; Gunnes, Gjermund; Press, Charles McLean; Rimstad, Espen; Koppang, Erling Olaf (Peer reviewed; Journal article, 2020)Farmed Atlantic salmon (Salmo salar) are prone to various conditions affecting the quality of the fillet. A well-known but so far poorly understood condition is the focal red changes in muscle, often referred to as ... -
Melanised focal changes in Atlantic salmon : interactions between infection and immunity
Bjørgen, Håvard (PhD Thesis;2021:82, Doctoral thesis, 2022)Atlantic salmon (Salmo salar) farming has increased rapidly in Norway over the last 50 years. However, the large-scale farming of salmon battles serious health problems. There are currently many adverse conditions threatening ... -
Melanized focal changes in skeletal muscle in farmed Atlantic salmon after natural infection with Piscine orthoreovirus (PRV)
Bjørgen, Håvard; Haldorsen, Randi; Oaland, Øyvind; Kvellestad, Agnar Ståle; Kannimuthu, Dhamotharan; Rimstad, Espen; Koppang, Erling Olaf (Journal article; Peer reviewed, 2019) -
Piscine orthoreovirus (PRV) in red and melanised foci in white muscle of Atlantic salmon (Salmo salar)
Bjørgen, Håvard; Wessel, Øystein; Fjelldal, Per Gunnar; Hansen, Tom Johnny; Sveier, Harald; Sæbø, Håkon Rydland; Enger, Katrine Bones; Monsen, Erik; Kvellestad, Agnar Ståle; Rimstad, Espen; Koppang, Erling Olaf (Journal article; Peer reviewed, 2015) -
PRV-1 Infected Macrophages in Melanized Focal Changes in White Muscle of Atlantic Salmon (Salmo salar) Correlates With a Pro-Inflammatory Environment
Malik, Muhammad Salman; Bjørgen, Håvard; Nyman, Ingvild Berg; Wessel, Øystein; Koppang, Erling Olaf; Dahle, Maria; Rimstad, Espen (Peer reviewed; Journal article, 2021) -
The teleost polymeric Ig receptor counterpart in ballan wrasse (Labrus bergylta) differs from pIgR in higher vertebrates
Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf; Hordvik, Ivar (Journal article; Peer reviewed, 2022) -
A teleost structural analogue to the avian bursa of Fabricius
Løken, Oskar Mongstad; Bjørgen, Håvard; Hordvik, Ivar; Koppang, Erling Olaf (Peer reviewed; Journal article, 2019)The bursa of Fabricius is a primary and secondary lymphoid organ considered exclusively present in birds, and studies of this structure have been vital to our current understanding of the adaptive immune system of vertebrates. ... -
Variations in mucous cell numbers in gills of Atlantic salmon (Salmo salar) presmolt in commercial freshwater farms in Norway
Persson, David Erik Ludvig; Bjørgen, Håvard; Figenschou, Alexander Joachim Hatchek; Hillestad, Linn-Anett; Koppang, Erling Olaf; Nødtvedt, Ane C. W.; Stormoen, Marit (Peer reviewed; Journal article, 2020)Fish gills are heavily exposed to the external milieu and may react against irritants with different cellular responses. We describe variations in mucous cell counts in gills from healthy Atlantic salmon (Salmo salar) ... -
Vertebral column deformity with curved cross-stitch vertebrae in Norwegian seawater-farmed Atlantic salmon, Salmo salar L.
Trangerud, Cathrine; Bjørgen, Håvard; Koppang, Erling Olaf; Grøntvedt, Randi; Skogmo, Hege Kippenes; Ottesen, Nina; Kvellestad, Agnar (Peer reviewed; Journal article, 2020)Pathological changes in the vertebral column of farmed Atlantic salmon in Norway have been reported since the 1990s. Based on the characteristic radiographic findings, we here present a vertebral column deformity named ...