Blar i Brage NMBU på forfatter "Tollefsen, Knut-Erik"
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Modes of action and adverse effects of gamma radiation in an aquatic macrophyte Lemna minor
Xie, Li; Solhaug, Knut Asbjørn; Song, You; Brede, Dag Anders; Lind, Ole Christian; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2019)High dose rates of ionizing radiation have been reported to cause adverse effects such as reduction in reproduction and growth, and damage to protein and lipids in primary producers. However, the relevant effects of ionizing ... -
Multiomics Point of Departure (moPOD) Modeling Supports an Adverse Outcome Pathway Network for Ionizing Radiation
Song, You; Zheng, Keke; Brede, Dag Anders; Gomes, Tania; Xie, Li; Kassaye, Yetneberk Ayalew; Salbu, Brit; Tollefsen, Knut-Erik (Journal article; Peer reviewed, 2023) -
De novo Development of a Quantitative Adverse Outcome Pathway (qAOP) Network for Ultraviolet B (UVB) Radiation Using Targeted Laboratory Tests and Automated Data Mining
Song, You; Xie, Li; Lee, YeonKyeong; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)Ultraviolet B (UVB) radiation is a natural non-chemical stressor posing potential hazards to organisms such as planktonic crustaceans. The present study was conducted to revisit the lethal effects of UVB on crustaceans, ... -
Oxidative stress potential of the herbicides bifenox and metribuzin in the microalgae Chlamydomonas reinhardtii
Almeida, Ana Catarina; Gomes, Tania; Langford, Katherine; Thomas, Kevin V; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2019)The widespread presence of herbicides in the aquatic environment has raised awareness about the need to develop further in depth ecotoxicological risk assessments, more specifically on potential effects on photosynthetic ... -
Pharmaceutical pollution: Prediction of environmental concentrations from national wholesales data
Welch, Samuel Alexander Stafford; Olsen, Kristine; Nouri Sharikabad, Mohammad; Tollefsen, Knut-Erik; Grung, Merete; Moe, Solveig Jannicke (Peer reviewed; Journal article, 2022) -
Predicting Environmental Risks of Pharmaceuticals from Wholesale Data: An Example from Norway
Welch, Samuel A.; Moe, S. Jannicke; Sharikabad, Mohammad Nouri; Tollefsen, Knut-Erik; Olsen, Kristine; Grung, Merete (Peer reviewed; Journal article, 2023) -
Probabilistic risk assessment of pesticides under future agricultural and climate scenarios using a bayesian network
Mentzel, Sophie; Grung, Merete; Holten, Roger; Tollefsen, Knut-Erik; Stenrød, Marianne; Moe, S. Jannicke (Peer reviewed; Journal article, 2022)The use of Bayesian networks (BN) for environmental risk assessment has increased in recent years as they offer a more transparent way to characterize risk and evaluate uncertainty than the traditional risk assessment ... -
Quantification of an Adverse Outcome Pathway Network by Bayesian Regression and Bayesian Network Modeling
Moe, S. Jannicke; Wolf, Raoul; Xie, Li; Landis, Wayne G.; Kotamäki, Niina; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2020)The adverse outcome pathway (AOP) framework has gained international recognition as a systematic approach linking mechanistic processes to toxicity endpoints. Nevertheless, successful implementation into risk assessments ... -
The MicroClimate Screen – A microscale climate exposure system for assessing the effect of CO2, temperature and UV on marine microalgae
Xie, Li; Macken, Ailbhe; Johnsen, Bjørn; Norli, Marit; Skogan, Odd Arne Segtnan; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2022)Global warming and anthropogenic activities are changing the ocean, inducing profound impacts on marine life and ecosystems from changing physical and chemical factors in and above the water column. Rising surface temperatures, ... -
Ultraviolet B modulates gamma radiation-induced stress responses in Lemna minor at multiple levels of biological organisation
Xie, Li; Song, You; Petersen, Karina; Solhaug, Knut Asbjørn; Lind, Ole Christian; Brede, Dag Anders; Salbu, Brit; Tollefsen, Knut-Erik (Peer reviewed; Journal article, 2022)Elevated levels of ionizing and non-ionizing radiation may co-occur and pose cumulative hazards to biota. However, the combined effects and underlying toxicity mechanisms of different types of radiation in aquatic plants ... -
Uranium accumulation and toxicokinetics in the crustacean Daphnia magna provide perspective to toxicodynamic responses
Scheibener, Shane; Song, You; Tollefsen, Knut-Erik; Salbu, Brit; Teien, Hans-Christian (Peer reviewed; Journal article, 2021)The importance of incorporating kinetic approaches in order to gain information on underlying physiological processes explaining species sensitivity to environmental stressors has been highlighted in recent years. Uranium ... -
Using a Bayesian Network Model to Predict Risk of Pesticides on Aquatic Community Endpoints in a Rice Field—A Southern European Case Study
Mentzel, Sophie; Martínez-Megías, Claudia; Grung, Merete; Rico, Andreu; Tollefsen, Knut-Erik; Van den Brink, Paul J.; Moe, S. Jannicke (Peer reviewed; Journal article, 2023)Bayesian network (BN) models are increasingly used as tools to support probabilistic environmental risk assessments (ERAs), because they can better account for uncertainty compared with the simpler approaches commonly used ...