Blar i Brage NMBU på forfatter "Straume, Daniel"
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Overuttrykk, rensing og karakterisering av CbpD : et nøkkelenzym for fratrisidmekanismen hos Streptococcus pneumoniae
Olsen, Silje (Master thesis, 2018)Streptococcus pneumoniae er en viktig humanpatogen bakterie, som har evnen til å bli kompetent for naturlig genetisk transformasjon. Dette gjør at den kan ta opp nakent DNA fra omgivelsene og inkorporere det i sitt eget ... -
Overuttrykk, rensing og karakterisering av fratrisinet CbpD fra Streptococcus dysgalactiae
Schultheiss, Anna Teigen (Master thesis, 2021)Streptococcus pneumoniae er en viktig humanpatogen. Mye forskning er derfor blitt utført på denne og nært beslektede streptokokker, men man har ikke like mye kunnskap om de mer perifere slektningene av denne bakterien, ... -
Prevention of EloR/KhpA heterodimerization by introduction of site-specific amino acid substitutions renders the essential elongasome protein PBP2b redundant in Streptococcus pneumoniae
Winther, Anja Ruud; Kjos, Morten; Stamsås, Gro Anita; Håvarstein, Leiv Sigve; Straume, Daniel (Peer reviewed; Journal article, 2019) -
Purification and characterization of streptovoracin, a novel antibiotic produced by a Pseudomonas species isolated from the Oslo fjord
Nesdal, Malene Tidemann (Master thesis, 2019)Antibiotikaresistent Streptococcus pneumoniae er en av de 18 største bakterielle truslene verden står ovenfor. Bakterien er alene ansvarlig for oppunder 2 millioner dødsfall hvert år på verdensbasis. På grunn av stadig ... -
Regulation of expression, purification and structural determination of the cross-wall splitting protein PcsB in Streptococcus pneumoniae
Stamsås, Gro Anita (PhD Thesis;2015:8, Doctoral thesis, 2018-04-24)The human pathogen Streptococcus pneumoniae causes approximately 1.6 million deaths per year. Hence, it is of great concern that the bacterium`s resistance against antibiotics has increased dramatically in recent decades. ... -
Rensing og karakterisering av colwellicin, et antimikrobielt stoff isolert fra Shewanella colwelliana
Fonn, Jeanette Stenersen (Master thesis, 2020)Da antibiotika ble introdusert på markedet, gav det håp om at infeksiøse sykdommer kunne bli bekjempet en gang for alle. Denne optimismen ble etter hvert overskygget av et økende antibiotikaresistensproblem. Resistensproblemet ... -
Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae
Alcorlo, Martín; Straume, Daniel; Lutkenhaus, Joe; Håvarstein, Leiv Sigve; Hermoso, Juan A. (Peer reviewed; Journal article, 2020)FtsEX is a membrane complex widely conserved across diverse bacterial genera and involved in critical processes such as recruitment of division proteins and in spatial and temporal regulation of muralytic activity during ... -
Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.
Morlot, Cécile; Straume, Daniel; Peters, Katharina; Hegnar, Olav Aaseth; Simon, Nolwenn; Villard, Anne-Maria; Contreras-Martel, Carlos; Leisico, Francisco; Breukink, Eefjan; Gravier-Pelletier, Christine; Le Corre, Laurent; Vollmer, Waldemar; Pietrancosta, Nicolas; Håvarstein, Leiv Sigve; Zapun, André (Journal article; Peer reviewed, 2018) -
Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae.
Rued, Britta E.; Alcorlo, Martín; Edmonds, Katherine A.; Martínez-Caballero, Siseth; Straume, Daniel; Fu, Yue; Bruce, Kevin E.; Wu, Hongwei; Håvarstein, Leiv Sigve; Hermoso, Juan A.; Winkler, Malcom E.; Giedroc, David P. (Peer reviewed; Journal article, 2019)Streptococcus pneumoniae is a leading killer of infants and immunocompromised adults and has become increasingly resistant to major antibiotics. Therefore, the development of new antibiotic strategies is desperately needed. ... -
The leaderless bacteriocin enterocin K1 is highly potent against Enterococcus faecium: A study on structure, target spectrum and receptor
Ovchinnikov, Kirill; Kristiansen, Per Eugen; Straume, Daniel; Jensen, Marianne Slang; Aleksandrzak-Piekarczyk, Tamara; Nes, Ingolf; Diep, Dzung Bao (Journal article; Peer reviewed, 2017) -
Uncovering a functional link between CozE proteins and lipoteichoic acid biosynthesis in Staphylococcus aureus
Barbuti, Maria Disen (Master thesis, 2021)Staphylococcus aureus is a common and successful human pathogen. Infections caused by S aureus have become an urgent challenge in nosocomial and community settings, due to their multiple virulence mechanisms and ability ...