Comparing different techniques for stimulating neurons - a computational study

Abstract

A comparison of different techniques for stimulating neurons using a computational model. The computational model is an expanded version of the electrodiffusive Pinsky-Rinzel model from Sætra et al. (2020) referenced in the thesis. The explicit modeling of ion concentrations allows for comparison of which ions are used for stimulation. The expansion of the model allows for comparison of stimulation currents coming from inside and outside the system. In conclusion, both the ion mix in the stimulation current and the stimulation technique can have an effect on the response of the model. In particular, there is an effect of potassium ions in the stimulation current.